Chromosomal localization of the gene encoding the human DNA helicase RECQL and its mouse homologue

Kasturi L. Puranam, Elizabeth Kennington, Sheila N.J.-Sait, Thomas B. Shows, Julie M. Rochelle, Michael F Seldin, Perry J. Blackshear

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

We have determined the chromosomal location of the human and mouse genes encoding the RECQL protein, a putative DNA helicase homologous to the bacterial DNA helicase, RecQ. RECQL was localized to human chromosome 12 by analysis of human-rodent somatic cell hybrid DNA; fine mapping of RECQL by fluorescence in situ hybridization revealed its chromosomal location to be 12p11-p12. The corresponding mouse gene, Recql, was mapped to the telomeric end of mouse chromosome 6 by analysis of DNA from an interspecific cross.

Original languageEnglish (US)
Pages (from-to)595-598
Number of pages4
JournalGenomics
Volume26
Issue number3
DOIs
StatePublished - Apr 10 1995
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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    Puranam, K. L., Kennington, E., N.J.-Sait, S., Shows, T. B., Rochelle, J. M., Seldin, M. F., & Blackshear, P. J. (1995). Chromosomal localization of the gene encoding the human DNA helicase RECQL and its mouse homologue. Genomics, 26(3), 595-598. https://doi.org/10.1016/0888-7543(95)80181-K