Chromosomal localization of the gene encoding the human DNA helicase RECQL and its mouse homologue

Kasturi L. Puranam; Elizabeth Kennington; Sheila N.J.-Sait; Thomas B. Shows; Julie M. Rochelle; Michael F Seldin; Perry J. Blackshear

doi:10.1016/0888-7543(95)80181-K

Chromosomal localization of the gene encoding the human DNA helicase RECQL and its mouse homologue

Kasturi L. Puranam, Elizabeth Kennington, Sheila N.J.-Sait, Thomas B. Shows, Julie M. Rochelle, Michael F Seldin, Perry J. Blackshear

Research output: Contribution to journal › Article

17 Scopus citations

Abstract

We have determined the chromosomal location of the human and mouse genes encoding the RECQL protein, a putative DNA helicase homologous to the bacterial DNA helicase, RecQ. RECQL was localized to human chromosome 12 by analysis of human-rodent somatic cell hybrid DNA; fine mapping of RECQL by fluorescence in situ hybridization revealed its chromosomal location to be 12p11-p12. The corresponding mouse gene, Recql, was mapped to the telomeric end of mouse chromosome 6 by analysis of DNA from an interspecific cross.

Original language	English (US)
Pages (from-to)	595-598
Number of pages	4
Journal	Genomics
Volume	26
Issue number	3
DOIs	https://doi.org/10.1016/0888-7543(95)80181-K
State	Published - Apr 10 1995
Externally published	Yes

ASJC Scopus subject areas

Genetics

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Puranam, K. L., Kennington, E., N.J.-Sait, S., Shows, T. B., Rochelle, J. M., Seldin, M. F., & Blackshear, P. J. (1995). Chromosomal localization of the gene encoding the human DNA helicase RECQL and its mouse homologue. Genomics, 26(3), 595-598. https://doi.org/10.1016/0888-7543(95)80181-K

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abstract = "We have determined the chromosomal location of the human and mouse genes encoding the RECQL protein, a putative DNA helicase homologous to the bacterial DNA helicase, RecQ. RECQL was localized to human chromosome 12 by analysis of human-rodent somatic cell hybrid DNA; fine mapping of RECQL by fluorescence in situ hybridization revealed its chromosomal location to be 12p11-p12. The corresponding mouse gene, Recql, was mapped to the telomeric end of mouse chromosome 6 by analysis of DNA from an interspecific cross.",

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AU - Shows, Thomas B.

AU - Rochelle, Julie M.

AU - Seldin, Michael F

AU - Blackshear, Perry J.

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AB - We have determined the chromosomal location of the human and mouse genes encoding the RECQL protein, a putative DNA helicase homologous to the bacterial DNA helicase, RecQ. RECQL was localized to human chromosome 12 by analysis of human-rodent somatic cell hybrid DNA; fine mapping of RECQL by fluorescence in situ hybridization revealed its chromosomal location to be 12p11-p12. The corresponding mouse gene, Recql, was mapped to the telomeric end of mouse chromosome 6 by analysis of DNA from an interspecific cross.

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