Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor

Satrajit Sinha; Sankar N. Maity; Michael F Seldin; Benoit De Crombrugghe

doi:10.1006/geno.1996.0555

Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor

Satrajit Sinha, Sankar N. Maity, Michael F Seldin, Benoit De Crombrugghe

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Abstract

The mammalian CCAAT-binding factor CBF (NFY) consists of three subunits, CBF-A, CBF-B, and CBF-C. All three subunits are evolutionarily conserved and are essential for DNA binding of CBF. In this study we report the identification of human and plant homologs of CBF-C. Northern analysis revealed that, like the other two subunits, CBF-C was produced at equal levels in all rat tissues that were examined. We assigned the mouse CBF-C gene (designated Nfyc) to chromosome 4 with tight linkage to Lmyc. Our mouse linkage data suggest that the human NFYC homolog will map to 1p32.

Original language	English (US)
Pages (from-to)	260-263
Number of pages	4
Journal	Genomics
Volume	37
Issue number	2
DOIs	https://doi.org/10.1006/geno.1996.0555
State	Published - Oct 15 1996
Externally published	Yes

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Genetics

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Sinha, S., Maity, S. N., Seldin, M. F., & De Crombrugghe, B. (1996). Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor. Genomics, 37(2), 260-263. https://doi.org/10.1006/geno.1996.0555

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10.1006/geno.1996.0555