TY - JOUR
T1 - Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor
AU - Sinha, Satrajit
AU - Maity, Sankar N.
AU - Seldin, Michael F
AU - De Crombrugghe, Benoit
PY - 1996/10/15
Y1 - 1996/10/15
N2 - The mammalian CCAAT-binding factor CBF (NFY) consists of three subunits, CBF-A, CBF-B, and CBF-C. All three subunits are evolutionarily conserved and are essential for DNA binding of CBF. In this study we report the identification of human and plant homologs of CBF-C. Northern analysis revealed that, like the other two subunits, CBF-C was produced at equal levels in all rat tissues that were examined. We assigned the mouse CBF-C gene (designated Nfyc) to chromosome 4 with tight linkage to Lmyc. Our mouse linkage data suggest that the human NFYC homolog will map to 1p32.
AB - The mammalian CCAAT-binding factor CBF (NFY) consists of three subunits, CBF-A, CBF-B, and CBF-C. All three subunits are evolutionarily conserved and are essential for DNA binding of CBF. In this study we report the identification of human and plant homologs of CBF-C. Northern analysis revealed that, like the other two subunits, CBF-C was produced at equal levels in all rat tissues that were examined. We assigned the mouse CBF-C gene (designated Nfyc) to chromosome 4 with tight linkage to Lmyc. Our mouse linkage data suggest that the human NFYC homolog will map to 1p32.
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U2 - 10.1006/geno.1996.0555
DO - 10.1006/geno.1996.0555
M3 - Article
C2 - 8921405
AN - SCOPUS:0030588143
VL - 37
SP - 260
EP - 263
JO - Genomics
JF - Genomics
SN - 0888-7543
IS - 2
ER -