Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor

Satrajit Sinha, Sankar N. Maity, Michael F Seldin, Benoit De Crombrugghe

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The mammalian CCAAT-binding factor CBF (NFY) consists of three subunits, CBF-A, CBF-B, and CBF-C. All three subunits are evolutionarily conserved and are essential for DNA binding of CBF. In this study we report the identification of human and plant homologs of CBF-C. Northern analysis revealed that, like the other two subunits, CBF-C was produced at equal levels in all rat tissues that were examined. We assigned the mouse CBF-C gene (designated Nfyc) to chromosome 4 with tight linkage to Lmyc. Our mouse linkage data suggest that the human NFYC homolog will map to 1p32.

Original languageEnglish (US)
Pages (from-to)260-263
Number of pages4
JournalGenomics
Volume37
Issue number2
DOIs
StatePublished - Oct 15 1996
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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