Abstract
The mammalian CCAAT-binding factor CBF (NFY) consists of three subunits, CBF-A, CBF-B, and CBF-C. All three subunits are evolutionarily conserved and are essential for DNA binding of CBF. In this study we report the identification of human and plant homologs of CBF-C. Northern analysis revealed that, like the other two subunits, CBF-C was produced at equal levels in all rat tissues that were examined. We assigned the mouse CBF-C gene (designated Nfyc) to chromosome 4 with tight linkage to Lmyc. Our mouse linkage data suggest that the human NFYC homolog will map to 1p32.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 260-263 |
| Number of pages | 4 |
| Journal | Genomics |
| Volume | 37 |
| Issue number | 2 |
| DOIs | |
| State | Published - Oct 15 1996 |
| Externally published | Yes |
ASJC Scopus subject areas
- Genetics
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Sinha, S., Maity, S. N., Seldin, M. F., & De Crombrugghe, B. (1996). Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor. Genomics, 37(2), 260-263. https://doi.org/10.1006/geno.1996.0555