Choreoathetosis developed in four of 21 children after the surgical repair of congenital cardiac anomalies with the use of circulatory arrest for 40 to 58 minutes at nasopharyngeal temperatures of 16 to 20°C. Choreoathetosis developing four to six days postoperatively was of varying severity and duration; only one patient had significant persiting dyskinesias. It is suggested that neuronal domage may have resulted from altered cerebrovascular reflow following circulatory arrest or from cintinued metabolism during the ischemia and hypoxia of the arrest period. Preoperative cerebral injury and altered blood viscosity during hypothermic perfusion may further predispose these patients to postoperative neurologic complications.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health