Choosing words

Left hemisphere, right hemisphere, or both? Perspective on the lateralization of word retrieval

Stéphanie K. Riès, Nina Dronkers, Robert T. Knight

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Language is considered to be one of the most lateralized human brain functions. Left hemisphere dominance for language has been consistently confirmed in clinical and experimental settings and constitutes one of the main axioms of neurology and neuroscience. However, functional neuroimaging studies are finding that the right hemisphere also plays a role in diverse language functions. Critically, the right hemisphere may also compensate for the loss or degradation of language functions following extensive stroke-induced damage to the left hemisphere. Here, we review studies that focus on our ability to choose words as we speak. Although fluidly performed in individuals with intact language, this process is routinely compromised in aphasic patients. We suggest that parceling word retrieval into its subprocesses-lexical activation and lexical selection-and examining which of these can be compensated for after left hemisphere stroke can advance the understanding of the lateralization of word retrieval in speech production. In particular, the domain-general nature of the brain regions associated with each process may be a helpful indicator of the right hemisphere's propensity for compensation.

Original languageEnglish (US)
JournalAnnals of the New York Academy of Sciences
DOIs
StateAccepted/In press - 2016

Fingerprint

Language
Brain
Functional neuroimaging
Neurology
Stroke
Chemical activation
Functional Neuroimaging
Aptitude
Degradation
Neurosciences
Right Hemisphere
Word Retrieval
Lateralization
Left Hemisphere
Functions of Language
Compensation and Redress
Propensity
Speech Production
Aphasic
Lexical Activation

Keywords

  • Compensatory mechanisms
  • Hemispheric lateralization
  • Language production
  • Stroke-induced aphasia
  • Word retrieval

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

Cite this

@article{3f1b71be83624e4c84f757371e75e267,
title = "Choosing words: Left hemisphere, right hemisphere, or both? Perspective on the lateralization of word retrieval",
abstract = "Language is considered to be one of the most lateralized human brain functions. Left hemisphere dominance for language has been consistently confirmed in clinical and experimental settings and constitutes one of the main axioms of neurology and neuroscience. However, functional neuroimaging studies are finding that the right hemisphere also plays a role in diverse language functions. Critically, the right hemisphere may also compensate for the loss or degradation of language functions following extensive stroke-induced damage to the left hemisphere. Here, we review studies that focus on our ability to choose words as we speak. Although fluidly performed in individuals with intact language, this process is routinely compromised in aphasic patients. We suggest that parceling word retrieval into its subprocesses-lexical activation and lexical selection-and examining which of these can be compensated for after left hemisphere stroke can advance the understanding of the lateralization of word retrieval in speech production. In particular, the domain-general nature of the brain regions associated with each process may be a helpful indicator of the right hemisphere's propensity for compensation.",
keywords = "Compensatory mechanisms, Hemispheric lateralization, Language production, Stroke-induced aphasia, Word retrieval",
author = "Ri{\`e}s, {St{\'e}phanie K.} and Nina Dronkers and Knight, {Robert T.}",
year = "2016",
doi = "10.1111/nyas.12993",
language = "English (US)",
journal = "Annals of the New York Academy of Sciences",
issn = "0077-8923",
publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Choosing words

T2 - Left hemisphere, right hemisphere, or both? Perspective on the lateralization of word retrieval

AU - Riès, Stéphanie K.

AU - Dronkers, Nina

AU - Knight, Robert T.

PY - 2016

Y1 - 2016

N2 - Language is considered to be one of the most lateralized human brain functions. Left hemisphere dominance for language has been consistently confirmed in clinical and experimental settings and constitutes one of the main axioms of neurology and neuroscience. However, functional neuroimaging studies are finding that the right hemisphere also plays a role in diverse language functions. Critically, the right hemisphere may also compensate for the loss or degradation of language functions following extensive stroke-induced damage to the left hemisphere. Here, we review studies that focus on our ability to choose words as we speak. Although fluidly performed in individuals with intact language, this process is routinely compromised in aphasic patients. We suggest that parceling word retrieval into its subprocesses-lexical activation and lexical selection-and examining which of these can be compensated for after left hemisphere stroke can advance the understanding of the lateralization of word retrieval in speech production. In particular, the domain-general nature of the brain regions associated with each process may be a helpful indicator of the right hemisphere's propensity for compensation.

AB - Language is considered to be one of the most lateralized human brain functions. Left hemisphere dominance for language has been consistently confirmed in clinical and experimental settings and constitutes one of the main axioms of neurology and neuroscience. However, functional neuroimaging studies are finding that the right hemisphere also plays a role in diverse language functions. Critically, the right hemisphere may also compensate for the loss or degradation of language functions following extensive stroke-induced damage to the left hemisphere. Here, we review studies that focus on our ability to choose words as we speak. Although fluidly performed in individuals with intact language, this process is routinely compromised in aphasic patients. We suggest that parceling word retrieval into its subprocesses-lexical activation and lexical selection-and examining which of these can be compensated for after left hemisphere stroke can advance the understanding of the lateralization of word retrieval in speech production. In particular, the domain-general nature of the brain regions associated with each process may be a helpful indicator of the right hemisphere's propensity for compensation.

KW - Compensatory mechanisms

KW - Hemispheric lateralization

KW - Language production

KW - Stroke-induced aphasia

KW - Word retrieval

UR - http://www.scopus.com/inward/record.url?scp=84954447835&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84954447835&partnerID=8YFLogxK

U2 - 10.1111/nyas.12993

DO - 10.1111/nyas.12993

M3 - Article

JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

SN - 0077-8923

ER -