Chlamydial endocervical infections and cytologic findings in sexually active female adolescents

Mary Ann Shafer, Karen L. Chew, Lois K. Kromhout, Arne Beck, Richard L Sweet, Julius Schachter, Eileen B. King

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The association of infection with Chlamydia trachomatis and cytologic changes on Papanicolaou smear was examined in 148 sexually active postmenarchal female subjects, aged 13 to 21 years (mean = 17.2) attending a teen clinic. Endocervical samples for micro-organisms (C. trachomatis and Neisseria gonorrhoeae) and a cervical sample for cytologic examination were taken. A detailed evaluation of the cytologic results was made independently of the C. trachomatis status. In 23 (15.5%) subjects tests for isolation of C. trachomatis were positive. Inflammatory changes in epithelial cells, nuclear changes in metaplastic cells, and lymphocytes in the inflammatory exudate were associated with C. trachomatis isolation but suspected "chlamydial inclusions" and cytoplasmic vacuoles in metaplastic cells were not. The results reported here do not support the use of cervical cytologic examination as a definitive diagnostic test for presence of an endocervical chlamydial infection. However, it may be possible to use the cytologic pattern described here to identify a population with a high prevalence of C. trachomatis.

Original languageEnglish (US)
Pages (from-to)765-771
Number of pages7
JournalAmerican Journal of Obstetrics and Gynecology
Volume151
Issue number6
DOIs
StatePublished - Mar 15 1985

Fingerprint

Chlamydia trachomatis
Infection
Papanicolaou Test
Neisseria gonorrhoeae
Inclusion Bodies
Exudates and Transudates
Vacuoles
Routine Diagnostic Tests
Epithelial Cells
Lymphocytes
Population

Keywords

  • Chlamydia trachomatis
  • culture
  • diagnosis
  • Papanicolaou smear

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Chlamydial endocervical infections and cytologic findings in sexually active female adolescents. / Shafer, Mary Ann; Chew, Karen L.; Kromhout, Lois K.; Beck, Arne; Sweet, Richard L; Schachter, Julius; King, Eileen B.

In: American Journal of Obstetrics and Gynecology, Vol. 151, No. 6, 15.03.1985, p. 765-771.

Research output: Contribution to journalArticle

Shafer, Mary Ann ; Chew, Karen L. ; Kromhout, Lois K. ; Beck, Arne ; Sweet, Richard L ; Schachter, Julius ; King, Eileen B. / Chlamydial endocervical infections and cytologic findings in sexually active female adolescents. In: American Journal of Obstetrics and Gynecology. 1985 ; Vol. 151, No. 6. pp. 765-771.
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