Childhood adversities and adult psychopathology in the WHO world mental health surveys

Ronald C. Kessler, Katie A. McLaughlin, Jennifer Greif Green, Michael J. Gruber, Nancy A. Sampson, Alan M. Zaslavsky, Sergio Aguilar-Gaxiola, Ali Obaid Alhamzawi, Jordi Alonso, Matthias Angermeyer, Corina Benjet, Evelyn Bromet, Somnath Chatterji, Giovanni De Girolamo, Koen Demyttenaere, John Fayyad, Silvia Florescu, Gilad Gal, Oye Gureje, Josep Maria Haro & 13 others Chi Yi Hu, Elie G. Karam, Norito Kawakami, Sing Lee, Jean Pierre Lépine, Johan Ormel, José Posada-Villa, Rajesh Sagar, Adley Tsang, T. Bedirhan Üstün, Svetlozar Vassilev, Maria Carmen Viana, David R. Williams

Research output: Contribution to journalArticle

740 Citations (Scopus)

Abstract

Background: Although significant associations of childhood adversities with adult mental disorders are widely documented, most studies focus on single childhood adversities predicting single disorders. Aims: To examine joint associations of 12 childhood adversities with first onset of 20 DSM-IV disorders in World Mental Health (WMH) Surveys in 21 countries. Method: Nationally or regionally representative surveys of 51 945 adults assessed childhood adversities and lifetime DSM-IV disorders with the WHO Composite International Diagnostic Interview (CIDI). Results: Childhood adversities were highly prevalent and interrelated. Childhood adversities associated with maladaptive family functioning (e.g. parental mental illness, child abuse, neglect) were the strongest predictors of disorders. Co-occurring childhood adversities associated with maladaptive family functioning had significant subadditive predictive associations and little specificity across disorders. Childhood adversities account for 29.8% of all disorders across countries. Conclusions: Childhood adversities have strong associations with all classes of disorders at all life-course stages in all groups of WMH countries. Long-term associations imply the existence of as-yet undetermined mediators.

Original languageEnglish (US)
Pages (from-to)378-385
Number of pages8
JournalBritish Journal of Psychiatry
Volume197
Issue number5
DOIs
StatePublished - Nov 2010

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Child Abuse
Health Surveys
Psychopathology
Diagnostic and Statistical Manual of Mental Disorders
Mental Health
Mental Disorders
Interviews
Global Health
Surveys and Questionnaires

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Kessler, R. C., McLaughlin, K. A., Green, J. G., Gruber, M. J., Sampson, N. A., Zaslavsky, A. M., ... Williams, D. R. (2010). Childhood adversities and adult psychopathology in the WHO world mental health surveys. British Journal of Psychiatry, 197(5), 378-385. https://doi.org/10.1192/bjp.bp.110.080499

Childhood adversities and adult psychopathology in the WHO world mental health surveys. / Kessler, Ronald C.; McLaughlin, Katie A.; Green, Jennifer Greif; Gruber, Michael J.; Sampson, Nancy A.; Zaslavsky, Alan M.; Aguilar-Gaxiola, Sergio; Alhamzawi, Ali Obaid; Alonso, Jordi; Angermeyer, Matthias; Benjet, Corina; Bromet, Evelyn; Chatterji, Somnath; De Girolamo, Giovanni; Demyttenaere, Koen; Fayyad, John; Florescu, Silvia; Gal, Gilad; Gureje, Oye; Haro, Josep Maria; Hu, Chi Yi; Karam, Elie G.; Kawakami, Norito; Lee, Sing; Lépine, Jean Pierre; Ormel, Johan; Posada-Villa, José; Sagar, Rajesh; Tsang, Adley; Bedirhan Üstün, T.; Vassilev, Svetlozar; Viana, Maria Carmen; Williams, David R.

In: British Journal of Psychiatry, Vol. 197, No. 5, 11.2010, p. 378-385.

Research output: Contribution to journalArticle

Kessler, RC, McLaughlin, KA, Green, JG, Gruber, MJ, Sampson, NA, Zaslavsky, AM, Aguilar-Gaxiola, S, Alhamzawi, AO, Alonso, J, Angermeyer, M, Benjet, C, Bromet, E, Chatterji, S, De Girolamo, G, Demyttenaere, K, Fayyad, J, Florescu, S, Gal, G, Gureje, O, Haro, JM, Hu, CY, Karam, EG, Kawakami, N, Lee, S, Lépine, JP, Ormel, J, Posada-Villa, J, Sagar, R, Tsang, A, Bedirhan Üstün, T, Vassilev, S, Viana, MC & Williams, DR 2010, 'Childhood adversities and adult psychopathology in the WHO world mental health surveys', British Journal of Psychiatry, vol. 197, no. 5, pp. 378-385. https://doi.org/10.1192/bjp.bp.110.080499
Kessler RC, McLaughlin KA, Green JG, Gruber MJ, Sampson NA, Zaslavsky AM et al. Childhood adversities and adult psychopathology in the WHO world mental health surveys. British Journal of Psychiatry. 2010 Nov;197(5):378-385. https://doi.org/10.1192/bjp.bp.110.080499
Kessler, Ronald C. ; McLaughlin, Katie A. ; Green, Jennifer Greif ; Gruber, Michael J. ; Sampson, Nancy A. ; Zaslavsky, Alan M. ; Aguilar-Gaxiola, Sergio ; Alhamzawi, Ali Obaid ; Alonso, Jordi ; Angermeyer, Matthias ; Benjet, Corina ; Bromet, Evelyn ; Chatterji, Somnath ; De Girolamo, Giovanni ; Demyttenaere, Koen ; Fayyad, John ; Florescu, Silvia ; Gal, Gilad ; Gureje, Oye ; Haro, Josep Maria ; Hu, Chi Yi ; Karam, Elie G. ; Kawakami, Norito ; Lee, Sing ; Lépine, Jean Pierre ; Ormel, Johan ; Posada-Villa, José ; Sagar, Rajesh ; Tsang, Adley ; Bedirhan Üstün, T. ; Vassilev, Svetlozar ; Viana, Maria Carmen ; Williams, David R. / Childhood adversities and adult psychopathology in the WHO world mental health surveys. In: British Journal of Psychiatry. 2010 ; Vol. 197, No. 5. pp. 378-385.
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abstract = "Background: Although significant associations of childhood adversities with adult mental disorders are widely documented, most studies focus on single childhood adversities predicting single disorders. Aims: To examine joint associations of 12 childhood adversities with first onset of 20 DSM-IV disorders in World Mental Health (WMH) Surveys in 21 countries. Method: Nationally or regionally representative surveys of 51 945 adults assessed childhood adversities and lifetime DSM-IV disorders with the WHO Composite International Diagnostic Interview (CIDI). Results: Childhood adversities were highly prevalent and interrelated. Childhood adversities associated with maladaptive family functioning (e.g. parental mental illness, child abuse, neglect) were the strongest predictors of disorders. Co-occurring childhood adversities associated with maladaptive family functioning had significant subadditive predictive associations and little specificity across disorders. Childhood adversities account for 29.8{\%} of all disorders across countries. Conclusions: Childhood adversities have strong associations with all classes of disorders at all life-course stages in all groups of WMH countries. Long-term associations imply the existence of as-yet undetermined mediators.",
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AU - Green, Jennifer Greif

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AU - Sampson, Nancy A.

AU - Zaslavsky, Alan M.

AU - Aguilar-Gaxiola, Sergio

AU - Alhamzawi, Ali Obaid

AU - Alonso, Jordi

AU - Angermeyer, Matthias

AU - Benjet, Corina

AU - Bromet, Evelyn

AU - Chatterji, Somnath

AU - De Girolamo, Giovanni

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AU - Fayyad, John

AU - Florescu, Silvia

AU - Gal, Gilad

AU - Gureje, Oye

AU - Haro, Josep Maria

AU - Hu, Chi Yi

AU - Karam, Elie G.

AU - Kawakami, Norito

AU - Lee, Sing

AU - Lépine, Jean Pierre

AU - Ormel, Johan

AU - Posada-Villa, José

AU - Sagar, Rajesh

AU - Tsang, Adley

AU - Bedirhan Üstün, T.

AU - Vassilev, Svetlozar

AU - Viana, Maria Carmen

AU - Williams, David R.

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