Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age

Giovanna Gatica-Domínguez; Stephen J. Rothenberg; Luisa Torres-Sánchez; María de Lourdes Schnaas; Rebecca Jean Schmidt; Lizbeth López-Carrillo

doi:10.21149/8581

Child dietary intake of folate and vitamin B₁₂ and their neurodevelopment at 24 and 30 months of age

Giovanna Gatica-Domínguez, Stephen J. Rothenberg, Luisa Torres-Sánchez, María de Lourdes Schnaas, Rebecca Jean Schmidt, Lizbeth López-Carrillo

Public Health Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Objective. To evaluate whether child dietary intake of folate and vitamin B₁₂, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B₁₂ at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95%CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B₁₂ with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.

Original language	English (US)
Pages (from-to)	388-394
Number of pages	7
Journal	Salud Publica de Mexico
Volume	60
Issue number	4
DOIs	https://doi.org/10.21149/8581
State	Published - Jul 1 2018

Keywords

Child development
Diet
Folic acid
Vitamin B

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health

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10.21149/8581

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Child dietary intake of folate and vitamin B₁₂ and their neurodevelopment at 24 and 30 months of age. / Gatica-Domínguez, Giovanna; Rothenberg, Stephen J.; Torres-Sánchez, Luisa; Schnaas, María de Lourdes; Schmidt, Rebecca Jean; López-Carrillo, Lizbeth.

In: Salud Publica de Mexico, Vol. 60, No. 4, 01.07.2018, p. 388-394.

Research output: Contribution to journal › Article › peer-review

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abstract = "Objective. To evaluate whether child dietary intake of folate and vitamin B12, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B12 at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95%CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B12 with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.",

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AU - Gatica-Domínguez, Giovanna

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AU - Torres-Sánchez, Luisa

AU - Schnaas, María de Lourdes

AU - Schmidt, Rebecca Jean

AU - López-Carrillo, Lizbeth

PY - 2018/7/1

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N2 - Objective. To evaluate whether child dietary intake of folate and vitamin B12, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B12 at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95%CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B12 with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.

AB - Objective. To evaluate whether child dietary intake of folate and vitamin B12, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B12 at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95%CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B12 with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.

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