TY - JOUR
T1 - Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age
AU - Gatica-Domínguez, Giovanna
AU - Rothenberg, Stephen J.
AU - Torres-Sánchez, Luisa
AU - Schnaas, María de Lourdes
AU - Schmidt, Rebecca Jean
AU - López-Carrillo, Lizbeth
PY - 2018/7/1
Y1 - 2018/7/1
N2 - Objective. To evaluate whether child dietary intake of folate and vitamin B12, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B12 at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95%CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B12 with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.
AB - Objective. To evaluate whether child dietary intake of folate and vitamin B12, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B12 at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95%CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B12 with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.
KW - Child development
KW - Diet
KW - Folic acid
KW - Vitamin B
UR - http://www.scopus.com/inward/record.url?scp=85049179817&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85049179817&partnerID=8YFLogxK
U2 - 10.21149/8581
DO - 10.21149/8581
M3 - Article
C2 - 30137940
AN - SCOPUS:85049179817
VL - 60
SP - 388
EP - 394
JO - Salud Publica de Mexico
JF - Salud Publica de Mexico
SN - 0036-3634
IS - 4
ER -