Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age

Giovanna Gatica-Domínguez, Stephen J. Rothenberg, Luisa Torres-Sánchez, María de Lourdes Schnaas, Rebecca Jean Schmidt, Lizbeth López-Carrillo

Research output: Contribution to journalArticle

Abstract

Objective. To evaluate whether child dietary intake of folate and vitamin B12, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B12 at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95%CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B12 with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.

Original languageEnglish (US)
Pages (from-to)388-394
Number of pages7
JournalSalud Publica de Mexico
Volume60
Issue number4
DOIs
StatePublished - Jul 1 2018

Fingerprint

Vitamin B 12
Folic Acid
Child Development
Food

Keywords

  • Child development
  • Diet
  • Folic acid
  • Vitamin B

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Gatica-Domínguez, G., Rothenberg, S. J., Torres-Sánchez, L., Schnaas, M. D. L., Schmidt, R. J., & López-Carrillo, L. (2018). Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age. Salud Publica de Mexico, 60(4), 388-394. https://doi.org/10.21149/8581

Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age. / Gatica-Domínguez, Giovanna; Rothenberg, Stephen J.; Torres-Sánchez, Luisa; Schnaas, María de Lourdes; Schmidt, Rebecca Jean; López-Carrillo, Lizbeth.

In: Salud Publica de Mexico, Vol. 60, No. 4, 01.07.2018, p. 388-394.

Research output: Contribution to journalArticle

Gatica-Domínguez, G, Rothenberg, SJ, Torres-Sánchez, L, Schnaas, MDL, Schmidt, RJ & López-Carrillo, L 2018, 'Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age', Salud Publica de Mexico, vol. 60, no. 4, pp. 388-394. https://doi.org/10.21149/8581
Gatica-Domínguez G, Rothenberg SJ, Torres-Sánchez L, Schnaas MDL, Schmidt RJ, López-Carrillo L. Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age. Salud Publica de Mexico. 2018 Jul 1;60(4):388-394. https://doi.org/10.21149/8581
Gatica-Domínguez, Giovanna ; Rothenberg, Stephen J. ; Torres-Sánchez, Luisa ; Schnaas, María de Lourdes ; Schmidt, Rebecca Jean ; López-Carrillo, Lizbeth. / Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age. In: Salud Publica de Mexico. 2018 ; Vol. 60, No. 4. pp. 388-394.
@article{30ef508bdad940bb98019c4c62fc3f8e,
title = "Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age",
abstract = "Objective. To evaluate whether child dietary intake of folate and vitamin B12, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B12 at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95{\%}CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B12 with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.",
keywords = "Child development, Diet, Folic acid, Vitamin B",
author = "Giovanna Gatica-Dom{\'i}nguez and Rothenberg, {Stephen J.} and Luisa Torres-S{\'a}nchez and Schnaas, {Mar{\'i}a de Lourdes} and Schmidt, {Rebecca Jean} and Lizbeth L{\'o}pez-Carrillo",
year = "2018",
month = "7",
day = "1",
doi = "10.21149/8581",
language = "English (US)",
volume = "60",
pages = "388--394",
journal = "Salud Publica de Mexico",
issn = "0036-3634",
publisher = "Instituto Nacional de Salud Publica",
number = "4",

}

TY - JOUR

T1 - Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age

AU - Gatica-Domínguez, Giovanna

AU - Rothenberg, Stephen J.

AU - Torres-Sánchez, Luisa

AU - Schnaas, María de Lourdes

AU - Schmidt, Rebecca Jean

AU - López-Carrillo, Lizbeth

PY - 2018/7/1

Y1 - 2018/7/1

N2 - Objective. To evaluate whether child dietary intake of folate and vitamin B12, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B12 at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95%CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B12 with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.

AB - Objective. To evaluate whether child dietary intake of folate and vitamin B12, is associated with mental and psychomotor development in Mexican children, respectively, at 24 and 30 months of age. Materials and methods. Information about neurodevelopment and dietary intake of folate and vitamin B12 at 24 and 30 months of age among 229 children belonging to a perinatal cohort was analyzed longitudinally. Dietary information was assessed using a semi-quantitative food frequency questionnaire, and neurodevelopment by Bayley Scale of Infant Development II. Results. At 30 months of age, dietary folate intake was marginally associated with increased Mental Development Index (MDI) (β=8.33; 95%CI -0.48, 17.14; p=0.06). Nonsignificant positive associations of vitamin B12 with MDI were found. Psychomotor Development Index (PDI) was not associated with these nutrients. Conclusion. Dietary folate intake in early childhood may benefit the mental development of children.

KW - Child development

KW - Diet

KW - Folic acid

KW - Vitamin B

UR - http://www.scopus.com/inward/record.url?scp=85049179817&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85049179817&partnerID=8YFLogxK

U2 - 10.21149/8581

DO - 10.21149/8581

M3 - Article

C2 - 30137940

AN - SCOPUS:85049179817

VL - 60

SP - 388

EP - 394

JO - Salud Publica de Mexico

JF - Salud Publica de Mexico

SN - 0036-3634

IS - 4

ER -