Abstract
Abstract: Nephrotoxicity is a common adverse effect of many chemotherapeutic agents. The agents most commonly associated with chemotherapy-associated nephrotoxicity are methotrexate, semustine, streptozocin, mithramycin, and cisplatin. Certain chemotherapeutic agents have adverse effects on the kidneys and urothelium that can be visualized radiographically, including cystic change, interstitial nephritis, papillary necrosis, urothelial changes, haemorrhagic cystitis, acute tubular necrosis, and infarction. This review focuses on imaging features identifying complications of chemotherapy in the kidneys and collecting system and provides didactic cases to alert referring clinicians. Teaching Points: • Nephrotoxicity is a common adverse effect of many chemotherapeutic agents. • Chemotherapies have adverse renal and urothelial effects that can be visualized radiographically. • Crizotinib use can result in the development of complex renal cysts.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 479-487 |
| Number of pages | 9 |
| Journal | Insights into Imaging |
| Volume | 6 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 29 2015 |
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Keywords
- Biologic agents
- Chemotherapy
- Drug-associated adverse effects
- Nephrotoxicity
- Renal cysts
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Chemotherapy-related complications in the kidneys and collecting system : an imaging perspective. / Jia, Jemianne Bautista; Lall, Chandana; Tirkes, Temel; Gulati, Rajesh; Lamba, Ramit; Goodwin, Scott C.
In: Insights into Imaging, Vol. 6, No. 4, 29.08.2015, p. 479-487.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Chemotherapy-related complications in the kidneys and collecting system
T2 - an imaging perspective
AU - Jia, Jemianne Bautista
AU - Lall, Chandana
AU - Tirkes, Temel
AU - Gulati, Rajesh
AU - Lamba, Ramit
AU - Goodwin, Scott C.
PY - 2015/8/29
Y1 - 2015/8/29
N2 - Abstract: Nephrotoxicity is a common adverse effect of many chemotherapeutic agents. The agents most commonly associated with chemotherapy-associated nephrotoxicity are methotrexate, semustine, streptozocin, mithramycin, and cisplatin. Certain chemotherapeutic agents have adverse effects on the kidneys and urothelium that can be visualized radiographically, including cystic change, interstitial nephritis, papillary necrosis, urothelial changes, haemorrhagic cystitis, acute tubular necrosis, and infarction. This review focuses on imaging features identifying complications of chemotherapy in the kidneys and collecting system and provides didactic cases to alert referring clinicians. Teaching Points: • Nephrotoxicity is a common adverse effect of many chemotherapeutic agents. • Chemotherapies have adverse renal and urothelial effects that can be visualized radiographically. • Crizotinib use can result in the development of complex renal cysts.
AB - Abstract: Nephrotoxicity is a common adverse effect of many chemotherapeutic agents. The agents most commonly associated with chemotherapy-associated nephrotoxicity are methotrexate, semustine, streptozocin, mithramycin, and cisplatin. Certain chemotherapeutic agents have adverse effects on the kidneys and urothelium that can be visualized radiographically, including cystic change, interstitial nephritis, papillary necrosis, urothelial changes, haemorrhagic cystitis, acute tubular necrosis, and infarction. This review focuses on imaging features identifying complications of chemotherapy in the kidneys and collecting system and provides didactic cases to alert referring clinicians. Teaching Points: • Nephrotoxicity is a common adverse effect of many chemotherapeutic agents. • Chemotherapies have adverse renal and urothelial effects that can be visualized radiographically. • Crizotinib use can result in the development of complex renal cysts.
KW - Biologic agents
KW - Chemotherapy
KW - Drug-associated adverse effects
KW - Nephrotoxicity
KW - Renal cysts
UR - http://www.scopus.com/inward/record.url?scp=84938366918&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84938366918&partnerID=8YFLogxK
U2 - 10.1007/s13244-015-0417-x
DO - 10.1007/s13244-015-0417-x
M3 - Article
AN - SCOPUS:84938366918
VL - 6
SP - 479
EP - 487
JO - Insights into Imaging
JF - Insights into Imaging
SN - 1869-4101
IS - 4
ER -