Chemotherapeutic interventions targeting HIV interactions with host-associated carbohydrates

Katherine D. McReynolds, Jacquelyn Gervay-Hague

Research output: Contribution to journalArticle

55 Scopus citations

Abstract

The host-associated carbohydrate-mediated entry processes of HIV-1 are reviewed. Topics covered include the current HIV/AIDS treatments and limitations, HIV-1 surface protein Gp 120 and its role in the viral entry of CD4-positive T-cells vial fusion, polyanionics polysaccharides as anti-HIV agents in CD4-positive cells, and HIV surface protein gp120 and its role in the viral entry of CD4-negative cells.

Original languageEnglish (US)
Pages (from-to)1533-1552
Number of pages20
JournalChemical Reviews
Volume107
Issue number5
DOIs
StatePublished - May 2007

ASJC Scopus subject areas

  • Chemistry(all)

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