Chemotherapeutic interventions targeting HIV interactions with host-associated carbohydrates

Katherine D. McReynolds; Jacquelyn Gervay-Hague

doi:10.1021/cr0502652

Chemotherapeutic interventions targeting HIV interactions with host-associated carbohydrates

Katherine D. McReynolds, Jacquelyn Gervay-Hague

Chemistry

Research output: Contribution to journal › Article

55 Scopus citations

Abstract

The host-associated carbohydrate-mediated entry processes of HIV-1 are reviewed. Topics covered include the current HIV/AIDS treatments and limitations, HIV-1 surface protein Gp 120 and its role in the viral entry of CD4-positive T-cells vial fusion, polyanionics polysaccharides as anti-HIV agents in CD4-positive cells, and HIV surface protein gp120 and its role in the viral entry of CD4-negative cells.

Original language	English (US)
Pages (from-to)	1533-1552
Number of pages	20
Journal	Chemical Reviews
Volume	107
Issue number	5
DOIs	https://doi.org/10.1021/cr0502652
Publication status	Published - May 2007

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ASJC Scopus subject areas

Chemistry(all)

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McReynolds, K. D., & Gervay-Hague, J. (2007). Chemotherapeutic interventions targeting HIV interactions with host-associated carbohydrates. Chemical Reviews, 107(5), 1533-1552. https://doi.org/10.1021/cr0502652

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Access to Document

10.1021/cr0502652