Chemoenzymatic synthesis of tumor-associated antigen N3 minor octasaccharide

Zhipeng Han, Congcong Chen, Caicai Meng, Tian Gao, Peng Peng, Xi Chen, Fengshan Wang, Hongzhi Cao

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A highly efficient chemoenzymatic approach was developed for the preparative scale synthesis of complex tumor-associated antigen N3 minor octasaccharide. The success of this approach relies on the highly efficient one-pot multi-enzyme based sequential enzymatic elongation of a chemically synthesized branched tetrasaccharide core structure.

Original languageEnglish (US)
Pages (from-to)412-422
Number of pages11
JournalJournal of Carbohydrate Chemistry
Issue number8-9
StatePublished - Nov 21 2016


  • Chemoenzymatic synthesis
  • glycosyltransferase
  • human milk oligosaccharide
  • N3 minor antigen

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry


Dive into the research topics of 'Chemoenzymatic synthesis of tumor-associated antigen N3 minor octasaccharide'. Together they form a unique fingerprint.

Cite this