Chelating agents for the binding of metal ions to macromolecules

M. W. Sundberg; C. F. Meares; D. A. Goodwin; C. I. Diamanti

doi:10.1038/250587a0

Chelating agents for the binding of metal ions to macromolecules

M. W. Sundberg, C. F. Meares, D. A. Goodwin, C. I. Diamanti

Chemistry

Research output: Contribution to journal › Article › peer-review

75 Scopus citations

Abstract

POLYAMINOCARBOXYLATE chelating agents such as ethylene-diaminetetraacetic acid (EDTA) form stable chelate complexes with the ions of many heavy metals. These metal ions exhibit a wide range of useful spectral and radioactive properties, such as electronic absorption, scattering of electrons and X rays, electron paramagnetic resonance spectra, the production of line-broadening and chemical shifts in nuclear magnetic resonance spectra, the emission of correlated gamma-ray cascades and various radioactive lifetimes and nuclear radiations. The preparation of chelating agents whose complexes can interact, in some selected manner, with biological macromolecules could make possible several new applications of metal ions as probes of biological systems.

Original language	English (US)
Pages (from-to)	587-588
Number of pages	2
Journal	Nature
Volume	250
Issue number	5467
DOIs	https://doi.org/10.1038/250587a0
State	Published - 1974

ASJC Scopus subject areas

General

Access to Document

10.1038/250587a0

Cite this

@article{6d1e86f771a24970b471443af86b5ea5,

title = "Chelating agents for the binding of metal ions to macromolecules",

abstract = "POLYAMINOCARBOXYLATE chelating agents such as ethylene-diaminetetraacetic acid (EDTA) form stable chelate complexes with the ions of many heavy metals. These metal ions exhibit a wide range of useful spectral and radioactive properties, such as electronic absorption, scattering of electrons and X rays, electron paramagnetic resonance spectra, the production of line-broadening and chemical shifts in nuclear magnetic resonance spectra, the emission of correlated gamma-ray cascades and various radioactive lifetimes and nuclear radiations. The preparation of chelating agents whose complexes can interact, in some selected manner, with biological macromolecules could make possible several new applications of metal ions as probes of biological systems.",

author = "Sundberg, {M. W.} and Meares, {C. F.} and Goodwin, {D. A.} and Diamanti, {C. I.}",

year = "1974",

doi = "10.1038/250587a0",

language = "English (US)",

volume = "250",

pages = "587--588",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Publishing Group",

number = "5467",

}

TY - JOUR

T1 - Chelating agents for the binding of metal ions to macromolecules

AU - Sundberg, M. W.

AU - Meares, C. F.

AU - Goodwin, D. A.

AU - Diamanti, C. I.

PY - 1974

Y1 - 1974

N2 - POLYAMINOCARBOXYLATE chelating agents such as ethylene-diaminetetraacetic acid (EDTA) form stable chelate complexes with the ions of many heavy metals. These metal ions exhibit a wide range of useful spectral and radioactive properties, such as electronic absorption, scattering of electrons and X rays, electron paramagnetic resonance spectra, the production of line-broadening and chemical shifts in nuclear magnetic resonance spectra, the emission of correlated gamma-ray cascades and various radioactive lifetimes and nuclear radiations. The preparation of chelating agents whose complexes can interact, in some selected manner, with biological macromolecules could make possible several new applications of metal ions as probes of biological systems.

AB - POLYAMINOCARBOXYLATE chelating agents such as ethylene-diaminetetraacetic acid (EDTA) form stable chelate complexes with the ions of many heavy metals. These metal ions exhibit a wide range of useful spectral and radioactive properties, such as electronic absorption, scattering of electrons and X rays, electron paramagnetic resonance spectra, the production of line-broadening and chemical shifts in nuclear magnetic resonance spectra, the emission of correlated gamma-ray cascades and various radioactive lifetimes and nuclear radiations. The preparation of chelating agents whose complexes can interact, in some selected manner, with biological macromolecules could make possible several new applications of metal ions as probes of biological systems.

UR - http://www.scopus.com/inward/record.url?scp=0016338647&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016338647&partnerID=8YFLogxK

U2 - 10.1038/250587a0

DO - 10.1038/250587a0

M3 - Article

C2 - 4210879

AN - SCOPUS:0016338647

VL - 250

SP - 587

EP - 588

JO - Nature

JF - Nature

SN - 0028-0836

IS - 5467

ER -

Chelating agents for the binding of metal ions to macromolecules

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this