Characterization of the LBNL PEM camera

G. C. Wang, J. S. Huber, W. W. Moses, J. Qi, W. S. Choong

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

We present the tomographic Images and performance measurements of the LBNL positron emission mammography (PEM) camera, a specially designed positron emission tomography (PET) camera that utilizes PET detector modules with depth of Interaction measurement capability to achieve both high sensitivity and high resolution for breast cancer detection. The camera currently consists of 24 detector modules positioned as four detector banks to cover a rectangular patient port that is 8.2 × 6 cm 2 with a 5 cm axial extent Each LBNL PEM detector module consists of 64 3 × 3 × 30 mm 3 LSO crystals coupled to a single photomultiplier tube (PMT) and an 8 × 8 silicon photodiode array (PD). The PMT provides accurate timing, the PD identifies the crystal of interaction, the sum of the PD and PMT signals (PD+PMT) provides the total energy, and the PD/(PD+PMT) ratio determines the depth of Interaction. The performance of the camera has been evaluated by imaging various phantoms. The full-width-at-hatf-maximum (FWHM) spatial resolution changes slightly from 1.9 mm to 2.1 mm when measured at the center and corner of the field of the view, respectively, using a 6 ns coincidence timing window and a 300-750 keV energy window. With the same setup, the peak sensitivity of the camera Is 1.83 kcps/μCi.

Original languageEnglish (US)
Article number1645006
Pages (from-to)1129-1135
Number of pages7
JournalIEEE Transactions on Nuclear Science
Volume53
Issue number3
DOIs
StatePublished - Jun 2006

Fingerprint

Mammography
Positrons
Photodiodes
Photomultipliers
photodiodes
photomultiplier tubes
positrons
Cameras
cameras
Detectors
Positron emission tomography
modules
detectors
tomography
time measurement
Crystals
sensitivity
interactions
breast
crystals

Keywords

  • Biomedical imaging
  • Depth of interaction (DOI)
  • Positron emission tomography (PET)

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Nuclear Energy and Engineering

Cite this

Wang, G. C., Huber, J. S., Moses, W. W., Qi, J., & Choong, W. S. (2006). Characterization of the LBNL PEM camera. IEEE Transactions on Nuclear Science, 53(3), 1129-1135. [1645006]. https://doi.org/10.1109/TNS.2006.874956

Characterization of the LBNL PEM camera. / Wang, G. C.; Huber, J. S.; Moses, W. W.; Qi, J.; Choong, W. S.

In: IEEE Transactions on Nuclear Science, Vol. 53, No. 3, 1645006, 06.2006, p. 1129-1135.

Research output: Contribution to journalArticle

Wang, GC, Huber, JS, Moses, WW, Qi, J & Choong, WS 2006, 'Characterization of the LBNL PEM camera', IEEE Transactions on Nuclear Science, vol. 53, no. 3, 1645006, pp. 1129-1135. https://doi.org/10.1109/TNS.2006.874956
Wang GC, Huber JS, Moses WW, Qi J, Choong WS. Characterization of the LBNL PEM camera. IEEE Transactions on Nuclear Science. 2006 Jun;53(3):1129-1135. 1645006. https://doi.org/10.1109/TNS.2006.874956
Wang, G. C. ; Huber, J. S. ; Moses, W. W. ; Qi, J. ; Choong, W. S. / Characterization of the LBNL PEM camera. In: IEEE Transactions on Nuclear Science. 2006 ; Vol. 53, No. 3. pp. 1129-1135.
@article{afe3613ed505473bbcef41f113865b69,
title = "Characterization of the LBNL PEM camera",
abstract = "We present the tomographic Images and performance measurements of the LBNL positron emission mammography (PEM) camera, a specially designed positron emission tomography (PET) camera that utilizes PET detector modules with depth of Interaction measurement capability to achieve both high sensitivity and high resolution for breast cancer detection. The camera currently consists of 24 detector modules positioned as four detector banks to cover a rectangular patient port that is 8.2 × 6 cm 2 with a 5 cm axial extent Each LBNL PEM detector module consists of 64 3 × 3 × 30 mm 3 LSO crystals coupled to a single photomultiplier tube (PMT) and an 8 × 8 silicon photodiode array (PD). The PMT provides accurate timing, the PD identifies the crystal of interaction, the sum of the PD and PMT signals (PD+PMT) provides the total energy, and the PD/(PD+PMT) ratio determines the depth of Interaction. The performance of the camera has been evaluated by imaging various phantoms. The full-width-at-hatf-maximum (FWHM) spatial resolution changes slightly from 1.9 mm to 2.1 mm when measured at the center and corner of the field of the view, respectively, using a 6 ns coincidence timing window and a 300-750 keV energy window. With the same setup, the peak sensitivity of the camera Is 1.83 kcps/μCi.",
keywords = "Biomedical imaging, Depth of interaction (DOI), Positron emission tomography (PET)",
author = "Wang, {G. C.} and Huber, {J. S.} and Moses, {W. W.} and J. Qi and Choong, {W. S.}",
year = "2006",
month = "6",
doi = "10.1109/TNS.2006.874956",
language = "English (US)",
volume = "53",
pages = "1129--1135",
journal = "IEEE Transactions on Nuclear Science",
issn = "0018-9499",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "3",

}

TY - JOUR

T1 - Characterization of the LBNL PEM camera

AU - Wang, G. C.

AU - Huber, J. S.

AU - Moses, W. W.

AU - Qi, J.

AU - Choong, W. S.

PY - 2006/6

Y1 - 2006/6

N2 - We present the tomographic Images and performance measurements of the LBNL positron emission mammography (PEM) camera, a specially designed positron emission tomography (PET) camera that utilizes PET detector modules with depth of Interaction measurement capability to achieve both high sensitivity and high resolution for breast cancer detection. The camera currently consists of 24 detector modules positioned as four detector banks to cover a rectangular patient port that is 8.2 × 6 cm 2 with a 5 cm axial extent Each LBNL PEM detector module consists of 64 3 × 3 × 30 mm 3 LSO crystals coupled to a single photomultiplier tube (PMT) and an 8 × 8 silicon photodiode array (PD). The PMT provides accurate timing, the PD identifies the crystal of interaction, the sum of the PD and PMT signals (PD+PMT) provides the total energy, and the PD/(PD+PMT) ratio determines the depth of Interaction. The performance of the camera has been evaluated by imaging various phantoms. The full-width-at-hatf-maximum (FWHM) spatial resolution changes slightly from 1.9 mm to 2.1 mm when measured at the center and corner of the field of the view, respectively, using a 6 ns coincidence timing window and a 300-750 keV energy window. With the same setup, the peak sensitivity of the camera Is 1.83 kcps/μCi.

AB - We present the tomographic Images and performance measurements of the LBNL positron emission mammography (PEM) camera, a specially designed positron emission tomography (PET) camera that utilizes PET detector modules with depth of Interaction measurement capability to achieve both high sensitivity and high resolution for breast cancer detection. The camera currently consists of 24 detector modules positioned as four detector banks to cover a rectangular patient port that is 8.2 × 6 cm 2 with a 5 cm axial extent Each LBNL PEM detector module consists of 64 3 × 3 × 30 mm 3 LSO crystals coupled to a single photomultiplier tube (PMT) and an 8 × 8 silicon photodiode array (PD). The PMT provides accurate timing, the PD identifies the crystal of interaction, the sum of the PD and PMT signals (PD+PMT) provides the total energy, and the PD/(PD+PMT) ratio determines the depth of Interaction. The performance of the camera has been evaluated by imaging various phantoms. The full-width-at-hatf-maximum (FWHM) spatial resolution changes slightly from 1.9 mm to 2.1 mm when measured at the center and corner of the field of the view, respectively, using a 6 ns coincidence timing window and a 300-750 keV energy window. With the same setup, the peak sensitivity of the camera Is 1.83 kcps/μCi.

KW - Biomedical imaging

KW - Depth of interaction (DOI)

KW - Positron emission tomography (PET)

UR - http://www.scopus.com/inward/record.url?scp=33746345596&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33746345596&partnerID=8YFLogxK

U2 - 10.1109/TNS.2006.874956

DO - 10.1109/TNS.2006.874956

M3 - Article

AN - SCOPUS:33746345596

VL - 53

SP - 1129

EP - 1135

JO - IEEE Transactions on Nuclear Science

JF - IEEE Transactions on Nuclear Science

SN - 0018-9499

IS - 3

M1 - 1645006

ER -