Abstract
We characterize the femtosecond laser-induced breakdown spectroscopy (fsLIBS) signal for biological tissues as a function of different excitation parameters with femtosecond laser systems. These parameters include laser energy, depth of focus, and number of pulses per focal volume. We used femtosecond laser pulses of 800 nm and energy between 25 and 123 ),J to generate LIBS signals in biological tissues. As expected, we observed a linear increase in the fsLIBS intensity as a function of the laser energy. In addition, we show that moving the beam out of focus and the presence of overlapping pulses on the same focal area leads to a decrease in fsLIBS intensity due to changes in focal spot size. We also demonstrate that fsLIBS can distinguish between different biological tissue samples.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 949-954 |
| Number of pages | 6 |
| Journal | Applied Spectroscopy |
| Volume | 68 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 1 2015 |
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Keywords
- Femtosecond phenomena
- Laser materials processing
- Laser-induced breakdown spectroscopy
- Libs
- Optical diagnostics for medicine chemical analysis
- Ultra-short pulsed laser
ASJC Scopus subject areas
- Spectroscopy
- Instrumentation
- Medicine(all)
Cite this
Characterization of femtosecond laser-induced breakdown spectroscopy (fsLIBS) and applications for biological samples. / Gill, Ruby K.; Knorr, Florian; Smith, Zachary J.; Kahraman, Mehmet; Madsen, Dorte; Larsen, Delmar S.; Wachsmann-Hogiu, Sebastian.
In: Applied Spectroscopy, Vol. 68, No. 9, 01.09.2015, p. 949-954.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Characterization of femtosecond laser-induced breakdown spectroscopy (fsLIBS) and applications for biological samples
AU - Gill, Ruby K.
AU - Knorr, Florian
AU - Smith, Zachary J.
AU - Kahraman, Mehmet
AU - Madsen, Dorte
AU - Larsen, Delmar S.
AU - Wachsmann-Hogiu, Sebastian
PY - 2015/9/1
Y1 - 2015/9/1
N2 - We characterize the femtosecond laser-induced breakdown spectroscopy (fsLIBS) signal for biological tissues as a function of different excitation parameters with femtosecond laser systems. These parameters include laser energy, depth of focus, and number of pulses per focal volume. We used femtosecond laser pulses of 800 nm and energy between 25 and 123 ),J to generate LIBS signals in biological tissues. As expected, we observed a linear increase in the fsLIBS intensity as a function of the laser energy. In addition, we show that moving the beam out of focus and the presence of overlapping pulses on the same focal area leads to a decrease in fsLIBS intensity due to changes in focal spot size. We also demonstrate that fsLIBS can distinguish between different biological tissue samples.
AB - We characterize the femtosecond laser-induced breakdown spectroscopy (fsLIBS) signal for biological tissues as a function of different excitation parameters with femtosecond laser systems. These parameters include laser energy, depth of focus, and number of pulses per focal volume. We used femtosecond laser pulses of 800 nm and energy between 25 and 123 ),J to generate LIBS signals in biological tissues. As expected, we observed a linear increase in the fsLIBS intensity as a function of the laser energy. In addition, we show that moving the beam out of focus and the presence of overlapping pulses on the same focal area leads to a decrease in fsLIBS intensity due to changes in focal spot size. We also demonstrate that fsLIBS can distinguish between different biological tissue samples.
KW - Femtosecond phenomena
KW - Laser materials processing
KW - Laser-induced breakdown spectroscopy
KW - Libs
KW - Optical diagnostics for medicine chemical analysis
KW - Ultra-short pulsed laser
UR - http://www.scopus.com/inward/record.url?scp=84928388149&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84928388149&partnerID=8YFLogxK
U2 - 10.1366/13-07293
DO - 10.1366/13-07293
M3 - Article
C2 - 25226248
AN - SCOPUS:84928388149
VL - 68
SP - 949
EP - 954
JO - Applied Spectroscopy
JF - Applied Spectroscopy
SN - 0003-7028
IS - 9
ER -