Characterization of an Anaplasma ovis isolate from desert bighorn sheep in southern California.

W. Goff, D. Stiller, D. Jessup, P. Msolla, Walter M Boyce, W. Foreyt

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


To understand the role of bighorn sheep (Ovis canadensis) in the epidemiology of anaplasmosis, we recovered a field isolate from a suspected enzootic area in southern California (USA). Whole blood was collected from three desert bighorn sheep (Ovis canadensis nelsoni) and inoculated into a susceptible splenectomized domestic sheep, calf and a susceptible spleen-intact bighorn sheep. No infection occurred in the calf, but a detectable infection developed in both the domestic sheep and bighorn sheep 24 days after inoculation. The infection in both domestic and bighorn sheep resulted in severe clinical disease but was resolved with the use of tetracycline. Using monoclonal antibodies and DNA probes, we confirmed that the isolate was Anaplasma ovis.

Original languageEnglish (US)
Pages (from-to)540-546
Number of pages7
JournalJournal of Wildlife Diseases
Issue number4
StatePublished - Oct 1993
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)


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