Characterization of a novel lytic protein encoded by the Bacillus cereus E33L gene ampD as a Bacillus anthracis antimicrobial protein

Feliza A. Bourguet, Brian E. Souza, Angela K. Hinz, Matthew A Coleman, Paul J. Jackson

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Lytic proteins encoded by bacterial genomes have been implicated in cell wall biosynthesis and recycling. The Bacillus cereus E33L ampD gene encodes a putative N-acetylmuramoyl-L-alanine amidase. This gene, expressed in vitro, produced a very stable, highly active lytic protein. Very low concentrations rapidly and efficiently lyse vegetative Bacillus anthracis cells.

Original languageEnglish (US)
Pages (from-to)3025-3027
Number of pages3
JournalApplied and Environmental Microbiology
Volume78
Issue number8
DOIs
StatePublished - Apr 2012
Externally publishedYes

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ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Food Science
  • Biotechnology
  • Ecology

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