Characteristics of long-term survivors of epithelial ovarian cancer

Rosemary D Cress, Yingjia S. Chen, Cyllene R. Morris, Megan Petersen, Gary S Leiserowitz

Research output: Contribution to journalArticle

75 Scopus citations

Abstract

OBJECTIVE: To identify characteristics associated with long-term survival for patients with epithelial ovarian cancer using the California Cancer Registry. METHODS: A descriptive analysis of survival of all California residents diagnosed with epithelial ovarian cancer between 1994 and 2001 was conducted using patients identified through the cancer registry with follow-up through 2011. Characteristics of the patients who survived more than 10 years (long-term survivors) were compared with three other cohorts: patients who survived less than 2 years, those who survived at least 2 but no more than 5 years, and those who survived at least 5 but no more than 10 years. RESULTS: A total of 3,582 out of 11,541 (31%, confidence interval 30.2-31.8%) of the patients survived more than 10 years. Younger age, early stage, low-grade, and nonserous histology were significant predictors of long-term survival, but long-term survivors also included women with high-risk cancer. CONCLUSION: Long-term survival is not unusual in patients with epithelial ovarian cancer, even in those with high-risk disease. Many of the prognostic factors are well known, but it remains to be determined why some patients with advanced-stage high-grade cancers survive longer than others with the same histology. These findings are important for patient counseling.

Original languageEnglish (US)
Pages (from-to)491-497
Number of pages7
JournalObstetrics and Gynecology
Volume126
Issue number3
DOIs
StatePublished - Sep 20 2015

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ASJC Scopus subject areas

  • Obstetrics and Gynecology

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