Abstract
Intracellular recordings were made from CA1 pyramidal cells in the hippocampal in vitro slice preparation. Neurons displayed characteristics previously described for the intact preparation including: EPSPs, IPSPs, depolarizing after-potentials, bursting, frequency potentiation, double pulse facilitation, and probable dendritic spiking. Cells could be discharged when orthodromic or antidromic pathways were stimulated, with injection of a depolarizing current pulse, and from iontophoresis of glutamic acid. The apparently normal behavior of the neurons makes the isolated hippocampal slice a promising cortical preparation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 423-436 |
| Number of pages | 14 |
| Journal | Brain Research |
| Volume | 85 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 7 1975 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)
Cite this
Characteristics of CA1 neurons recorded intracellularly in the hippocampal in vitro slice preparation. / Schwartzkroin, Philip A.
In: Brain Research, Vol. 85, No. 3, 07.03.1975, p. 423-436.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Characteristics of CA1 neurons recorded intracellularly in the hippocampal in vitro slice preparation
AU - Schwartzkroin, Philip A
PY - 1975/3/7
Y1 - 1975/3/7
N2 - Intracellular recordings were made from CA1 pyramidal cells in the hippocampal in vitro slice preparation. Neurons displayed characteristics previously described for the intact preparation including: EPSPs, IPSPs, depolarizing after-potentials, bursting, frequency potentiation, double pulse facilitation, and probable dendritic spiking. Cells could be discharged when orthodromic or antidromic pathways were stimulated, with injection of a depolarizing current pulse, and from iontophoresis of glutamic acid. The apparently normal behavior of the neurons makes the isolated hippocampal slice a promising cortical preparation.
AB - Intracellular recordings were made from CA1 pyramidal cells in the hippocampal in vitro slice preparation. Neurons displayed characteristics previously described for the intact preparation including: EPSPs, IPSPs, depolarizing after-potentials, bursting, frequency potentiation, double pulse facilitation, and probable dendritic spiking. Cells could be discharged when orthodromic or antidromic pathways were stimulated, with injection of a depolarizing current pulse, and from iontophoresis of glutamic acid. The apparently normal behavior of the neurons makes the isolated hippocampal slice a promising cortical preparation.
UR - http://www.scopus.com/inward/record.url?scp=0016640871&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0016640871&partnerID=8YFLogxK
U2 - 10.1016/0006-8993(75)90817-3
DO - 10.1016/0006-8993(75)90817-3
M3 - Article
C2 - 1111846
AN - SCOPUS:0016640871
VL - 85
SP - 423
EP - 436
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 3
ER -