Abstract
Intracellular recordings were made from CA1 pyramidal cells in the hippocampal in vitro slice preparation. Neurons displayed characteristics previously described for the intact preparation including: EPSPs, IPSPs, depolarizing after-potentials, bursting, frequency potentiation, double pulse facilitation, and probable dendritic spiking. Cells could be discharged when orthodromic or antidromic pathways were stimulated, with injection of a depolarizing current pulse, and from iontophoresis of glutamic acid. The apparently normal behavior of the neurons makes the isolated hippocampal slice a promising cortical preparation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 423-436 |
| Number of pages | 14 |
| Journal | Brain Research |
| Volume | 85 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 7 1975 |
| Externally published | Yes |
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)