Abstract
Intracellular recordings were made from CA1 pyramidal cells in the hippocampal in vitro slice preparation. Neurons displayed characteristics previously described for the intact preparation including: EPSPs, IPSPs, depolarizing after-potentials, bursting, frequency potentiation, double pulse facilitation, and probable dendritic spiking. Cells could be discharged when orthodromic or antidromic pathways were stimulated, with injection of a depolarizing current pulse, and from iontophoresis of glutamic acid. The apparently normal behavior of the neurons makes the isolated hippocampal slice a promising cortical preparation.
Original language | English (US) |
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Pages (from-to) | 423-436 |
Number of pages | 14 |
Journal | Brain Research |
Volume | 85 |
Issue number | 3 |
DOIs | |
State | Published - Mar 7 1975 |
Externally published | Yes |
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)