Abstract
Objective: Limited joint mobility (LJM), the earliest clinically apparent long-term complication of type 1 diabetes mellitus, is a risk indicator for microvascular complications, and its appearance is primarily affected by long-term metabolic control. We hypothesized that the prevalence of LJM had decreased during the past 20 years. Study design: We examined 312 subjects with type I diabetes mellitus, aged 7 to 18 years, using the same examination method and criteria as in studies of 515 subjects in this age group carried out between 1976 and 1978 for whom primary data were available, including age, duration of diabetes, and LJM stage. Statistical analyses included exact X2 tests, independent sample t tests, and unconditional logistic regression. Results: There was a >4-fold reduction in frequency of LJM between 1976-78 and 1998 (31% vs 7%, P < .001), with a decrease in the proportion having moderate or severe LJM (35% vs 9%, P = .025). Conclusions: These findings confirm the hypothesis that the prevalence of LJM has decreased, most likely the result of improved blood glucose control during the past 2 decades.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 33-37 |
| Number of pages | 5 |
| Journal | Journal of Pediatrics |
| Volume | 138 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2001 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
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Changes in frequency and severity of limited joint mobility in children with type 1 diabetes mellitus between 1976-78 and 1998. / Infante, Jeffrey R.; Rosenbloom, Arlan L.; Silverstein, Janet H.; Garzarella, Linda; Pollock, Bradley H.
In: Journal of Pediatrics, Vol. 138, No. 1, 2001, p. 33-37.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Changes in frequency and severity of limited joint mobility in children with type 1 diabetes mellitus between 1976-78 and 1998
AU - Infante, Jeffrey R.
AU - Rosenbloom, Arlan L.
AU - Silverstein, Janet H.
AU - Garzarella, Linda
AU - Pollock, Bradley H
PY - 2001
Y1 - 2001
N2 - Objective: Limited joint mobility (LJM), the earliest clinically apparent long-term complication of type 1 diabetes mellitus, is a risk indicator for microvascular complications, and its appearance is primarily affected by long-term metabolic control. We hypothesized that the prevalence of LJM had decreased during the past 20 years. Study design: We examined 312 subjects with type I diabetes mellitus, aged 7 to 18 years, using the same examination method and criteria as in studies of 515 subjects in this age group carried out between 1976 and 1978 for whom primary data were available, including age, duration of diabetes, and LJM stage. Statistical analyses included exact X2 tests, independent sample t tests, and unconditional logistic regression. Results: There was a >4-fold reduction in frequency of LJM between 1976-78 and 1998 (31% vs 7%, P < .001), with a decrease in the proportion having moderate or severe LJM (35% vs 9%, P = .025). Conclusions: These findings confirm the hypothesis that the prevalence of LJM has decreased, most likely the result of improved blood glucose control during the past 2 decades.
AB - Objective: Limited joint mobility (LJM), the earliest clinically apparent long-term complication of type 1 diabetes mellitus, is a risk indicator for microvascular complications, and its appearance is primarily affected by long-term metabolic control. We hypothesized that the prevalence of LJM had decreased during the past 20 years. Study design: We examined 312 subjects with type I diabetes mellitus, aged 7 to 18 years, using the same examination method and criteria as in studies of 515 subjects in this age group carried out between 1976 and 1978 for whom primary data were available, including age, duration of diabetes, and LJM stage. Statistical analyses included exact X2 tests, independent sample t tests, and unconditional logistic regression. Results: There was a >4-fold reduction in frequency of LJM between 1976-78 and 1998 (31% vs 7%, P < .001), with a decrease in the proportion having moderate or severe LJM (35% vs 9%, P = .025). Conclusions: These findings confirm the hypothesis that the prevalence of LJM has decreased, most likely the result of improved blood glucose control during the past 2 decades.
UR - http://www.scopus.com/inward/record.url?scp=0035145556&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035145556&partnerID=8YFLogxK
U2 - 10.1067/mpd.2001.109710
DO - 10.1067/mpd.2001.109710
M3 - Article
C2 - 11148509
AN - SCOPUS:0035145556
VL - 138
SP - 33
EP - 37
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 1
ER -