Cerebrovascular Disease

C. DeCarli, S. N. Lockhart

Research output: Chapter in Book/Report/Conference proceedingChapter


Advancing age is associated with declines in cognitive ability. Incident disease often occurs concurrent to these cognitive declines, particularly Alzheimer's disease (AD). Consequently, AD has been ascribed as the cause for much of the cognitive impairment associated with advancing age. Vascular risk factors such as obesity, hypertension, and diabetes are common and often present for decades before the age of risk for cognitive decline. In this article, evidence that vascular risk factors are an important and modifiable risk for later-life cognitive impairment is reviewed.

Original languageEnglish (US)
Title of host publicationEncyclopedia of the Neurological Sciences
PublisherElsevier Inc.
Number of pages5
ISBN (Electronic)9780123851574
ISBN (Print)9780123851581
StatePublished - Jan 1 2014


  • Aging
  • Alzheimer's disease
  • Brain imaging
  • Magnetic resonance imaging (MRI)
  • Pathology
  • Positron emission tomography
  • Stroke
  • Vascular disease
  • Vascular risk factors
  • White matter hyperintensities
  • X-ray computed tomography

ASJC Scopus subject areas

  • Medicine(all)


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