Abstract
PURPOSE: To assess the utility of magnetic resonance (MR) cerebral blood volume (CBV) maps in the evaluation of gliomas. MATERIALS AND METHODS: CBV maps from 19 patients with histologically proved gliomas were calculated from dynamic MR image sets acquired with echo-planar spin-echo imaging after intravenous injection of gadolinium-based contrast material. RESULTS: The maximum CBV varied from 0.82 to 5.40 in the high-grade group (n = 13) and from 1.01 to 1.21 in the low-grade group (n = 6). The difference was statistically significant. Maximum CBV was associated with mitotic activity and vascularity, but not with cellular atypia, endothelial proliferation, necrosis, or cellularity. CONCLUSION: MR CBV maps provided diagnostic information not available with conventional MR imaging in six cases and offers a functional parameter for assessing glioma grade and regions of focal activity.
Original language | English (US) |
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Pages (from-to) | 41-51 |
Number of pages | 11 |
Journal | RADIOLOGY |
Volume | 191 |
Issue number | 1 |
DOIs | |
State | Published - 1994 |
Externally published | Yes |
Keywords
- Brain neoplasms
- Magnetic resonance (MR), echo planar
- Magnetic resonance (MR), vascular studies
- Magnetic resonance (MR), volume measurement
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging