Abstract
Cerebral blood flow mapping with stable xenon-enhanced computed tomography (Xe/CT) was performed in conjunction with conventional computed tomography (CT) within the first 8 hours after the onset of symptoms in seven patients with cerebral infarction. Six patients had hemispheric infarctions, and one had a progressive brainstem infarction. Three patients with very low (<10 ml/100 g/min) blood flow in an anatomic area appropriate for the neurologic deficit had no clinical improvement by the time of discharge from the hospital; follow-up CT scans of these three patients confirmed infarction in the area of very low blood flow. Three patients with moderate blood flow reductions (15-45 ml/100 g/min) in the appropriate anatomic area had significant clinical improvement from their initial deficits and had normal follow-up CT scans. One patient studied 8 hours after stroke had increased blood flow (hyperemia) in the appropriate anatomic area and made no clinical recovery.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 754-760 |
| Number of pages | 7 |
| Journal | Stroke |
| Volume | 20 |
| Issue number | 6 |
| State | Published - 1989 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Neuroscience(all)
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Cerebral blood flow determination within the first 8 hours of cerebral infarction using stable xenon-enhanced computed tomography. / Hughes, R. L.; Yonas, H.; Gur, D.; Latchaw, Richard E.
In: Stroke, Vol. 20, No. 6, 1989, p. 754-760.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Cerebral blood flow determination within the first 8 hours of cerebral infarction using stable xenon-enhanced computed tomography
AU - Hughes, R. L.
AU - Yonas, H.
AU - Gur, D.
AU - Latchaw, Richard E
PY - 1989
Y1 - 1989
N2 - Cerebral blood flow mapping with stable xenon-enhanced computed tomography (Xe/CT) was performed in conjunction with conventional computed tomography (CT) within the first 8 hours after the onset of symptoms in seven patients with cerebral infarction. Six patients had hemispheric infarctions, and one had a progressive brainstem infarction. Three patients with very low (<10 ml/100 g/min) blood flow in an anatomic area appropriate for the neurologic deficit had no clinical improvement by the time of discharge from the hospital; follow-up CT scans of these three patients confirmed infarction in the area of very low blood flow. Three patients with moderate blood flow reductions (15-45 ml/100 g/min) in the appropriate anatomic area had significant clinical improvement from their initial deficits and had normal follow-up CT scans. One patient studied 8 hours after stroke had increased blood flow (hyperemia) in the appropriate anatomic area and made no clinical recovery.
AB - Cerebral blood flow mapping with stable xenon-enhanced computed tomography (Xe/CT) was performed in conjunction with conventional computed tomography (CT) within the first 8 hours after the onset of symptoms in seven patients with cerebral infarction. Six patients had hemispheric infarctions, and one had a progressive brainstem infarction. Three patients with very low (<10 ml/100 g/min) blood flow in an anatomic area appropriate for the neurologic deficit had no clinical improvement by the time of discharge from the hospital; follow-up CT scans of these three patients confirmed infarction in the area of very low blood flow. Three patients with moderate blood flow reductions (15-45 ml/100 g/min) in the appropriate anatomic area had significant clinical improvement from their initial deficits and had normal follow-up CT scans. One patient studied 8 hours after stroke had increased blood flow (hyperemia) in the appropriate anatomic area and made no clinical recovery.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024392015&partnerID=8YFLogxK
M3 - Article
C2 - 2728041
AN - SCOPUS:0024392015
VL - 20
SP - 754
EP - 760
JO - Stroke
JF - Stroke
SN - 0039-2499
IS - 6
ER -