Cellular immunologic studies of malignant lymphoma in rhesus macaques.

C. A. Holmberg, Bennie Osburn, T. G. Terrell, J. S. Manning

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Cells from malignant lymphoma in 10 rhesus macaques were examined for lymphocyte surface markers. Three had features of T cells, 5 had features of B cells, and 2 lacked evidence of either B- or T-cell differentiation. Correlation between the histologic classification of cell type and the B- or T-cell nature of the neoplasms was not evident. Evaluation of serum electrophoresis, mitogen responses tests, and previous histologic studies suggest that the development of the neoplastic lymphocyte proliferation occurred following or during an abnormal immunologic response.

Original languageEnglish (US)
Pages (from-to)469-472
Number of pages4
JournalAmerican Journal of Veterinary Research
Issue number3
StatePublished - Mar 1 1978
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)


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