Cell signaling in yeast sporulation

JoAnne Engebrecht

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Gametogenesis is essential for the propagation of all sexually reproducing organisms and consists of halving the chromosome number through meiosis, and the subsequent packaging of the haploid products into gametes. Meiosis and gamete formation must be tightly coupled to ensure the formation of viable progeny; perturbations result in infertility, inviability, and birth defects. In the yeast Saccharomyces cerevisiae, sexual reproduction occurs via sporulation and is similar in many respects to gametogenesis in mammals. An increasing number of conserved signaling molecules have been shown to be essential for yeast sporulation; recent studies reveal molecular insights into how these molecules regulate this intricate differentiation program.

Original languageEnglish (US)
Pages (from-to)325-328
Number of pages4
JournalBiochemical and Biophysical Research Communications
Issue number2
StatePublished - Jun 27 2003
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology


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