Cell polarity: Tension quenches the rear

Alex Mogilner, Jie Zhu

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


A combination of biophysical perturbations and computer simulations shows that leading edge protrusion in crawling cells increases membrane tension, which constrains the protruding front to one side of the cell, thereby maintaining its polarity.

Original languageEnglish (US)
JournalCurrent Biology
Issue number2
StatePublished - Jan 24 2012

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)


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