Cefotetan in the treatment of obstetric and gynecologic infections

Alfred N. Poindexter, Richard L Sweet, Marcella Ritter

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The efficacy, tolerance, and safety of cefotetan-a new 7-α-methoxy cephalosporin-was assessed in controlled and uncontrolled evaluations involving 131 evaluable patients hospitalized with obstetric and gynecologic infections. The 99% satisfactory clinical response rate obtained with this drug was equivalent to that obtained with either moxalactam or cefoxitin, yet the mean amount of cefotetan given was lower than that of the other two drugs. Cefotetan was well tolerated and produced no major adverse reactions. In this era of Diagnosis Related Groups and cost containment, the twice-daily dosage schedule of cefotetan is a decided cost benefit.

Original languageEnglish (US)
Pages (from-to)946-950
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Volume154
Issue number4
DOIs
StatePublished - 1986

Keywords

  • antibiotics
  • Cefotetan
  • endometritis
  • pelvic inflammatory disease

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

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