CdTe strip detector characterization for high resolution small animal PET

Gregory Mitchell, Shrabani Sinha, Jennifer R. Stickel, Spencer L. Bowen, Leonard J. Cirignano, Purushottam Dokhale, Hadong Kim, Kanai S. Shah, Simon R Cherry

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Excellent spatial resolution is a requirement for preclinical PET imaging. In order to achieve spatial resolution of significantly better than one millimeter, an appealing possibility is to employ direct detector materials, such as cadmium telluride (CdTe). Prototype thin orthogonal strip detectors have been developed for testing. They have dimensions of 20 mm by 20 mm and are 0.5 mm thick, and have strips of 0.5 mm pitch on one side and 2.5 mm pitch on the other. Results are presented for the energy resolution (3% at 511 keV), intrinsic position resolution (equal to the 0.5 mm strip pitch), and timing resolution (3 ns FWHM in coincidence with an LSO detector, 8 ns FWHM for coincidence of two CdTe detectors) of the detectors. A PET scanner design is proposed using blocks made of the CdTe strip detectors, oriented in the blocks with their thin edges toward the center of the scanner. Simulation results suggest that this scanner, using a threshold of 250 keV, would have a sensitivity of 3.4% for a point source at its center.

Original languageEnglish (US)
Article number4545167
Pages (from-to)870-876
Number of pages7
JournalIEEE Transactions on Nuclear Science
Volume55
Issue number3
DOIs
StatePublished - Jun 2008

Fingerprint

Cadmium telluride
cadmium tellurides
animals
strip
Animals
Detectors
high resolution
detectors
scanners
Full width at half maximum
spatial resolution
point sources
prototypes
time measurement
Imaging techniques
requirements
thresholds
sensitivity
Testing

Keywords

  • Cadmium telluride (CdTe)
  • Positron emission tomography (PET)
  • Small animal imaging

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Nuclear Energy and Engineering

Cite this

CdTe strip detector characterization for high resolution small animal PET. / Mitchell, Gregory; Sinha, Shrabani; Stickel, Jennifer R.; Bowen, Spencer L.; Cirignano, Leonard J.; Dokhale, Purushottam; Kim, Hadong; Shah, Kanai S.; Cherry, Simon R.

In: IEEE Transactions on Nuclear Science, Vol. 55, No. 3, 4545167, 06.2008, p. 870-876.

Research output: Contribution to journalArticle

Mitchell, G, Sinha, S, Stickel, JR, Bowen, SL, Cirignano, LJ, Dokhale, P, Kim, H, Shah, KS & Cherry, SR 2008, 'CdTe strip detector characterization for high resolution small animal PET', IEEE Transactions on Nuclear Science, vol. 55, no. 3, 4545167, pp. 870-876. https://doi.org/10.1109/TNS.2008.922800
Mitchell, Gregory ; Sinha, Shrabani ; Stickel, Jennifer R. ; Bowen, Spencer L. ; Cirignano, Leonard J. ; Dokhale, Purushottam ; Kim, Hadong ; Shah, Kanai S. ; Cherry, Simon R. / CdTe strip detector characterization for high resolution small animal PET. In: IEEE Transactions on Nuclear Science. 2008 ; Vol. 55, No. 3. pp. 870-876.
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