Abstract
From 1993 to 1995, approximately 10% of the clinically healthy northern elephant seals (Mirounga angustirostris) at The Marine Mammal Center in California exhibited a large unexplained increase in their white blood cell (WBC) count. In these animals, WBC counts ranged from 28,780 to 125,000/mm3, with a mean of 50,087/mm3. Significant correlations between the leukocytosis and weight gain and day of admittance were identified, but no correlation existed between leukocytosis and general state of health, sex, length of stay, or diet. Bone marrow contamination of blood samples, erroneous automated leukocyte counts, and leukogram changes consistent with subclinical inflammation were the major factors contributing to the elevated WBC counts in these apparently clinically healthy animals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 408-412 |
| Number of pages | 5 |
| Journal | Journal of Zoo and Wildlife Medicine |
| Volume | 29 |
| Issue number | 4 |
| State | Published - Dec 1998 |
| Externally published | Yes |
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Keywords
- Bone marrow contamination
- Extradural intravertebral vein
- Mirounga angustirostris
- Northern elephant seal
- Serial blood samples
- Spurious leukocytosis
ASJC Scopus subject areas
- Animal Science and Zoology
- Environmental Science(all)
- veterinary(all)
Cite this
Causes of erroneous white blood cell counts and differentials in clinically healthy young northern elephant seals (Mirounga angustirostris). / Goldstein, Tracey; Johnson, Shawn P.; Werner, Linda J.; Nolan, Sherry; Hilliard, Bobby A.
In: Journal of Zoo and Wildlife Medicine, Vol. 29, No. 4, 12.1998, p. 408-412.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Causes of erroneous white blood cell counts and differentials in clinically healthy young northern elephant seals (Mirounga angustirostris)
AU - Goldstein, Tracey
AU - Johnson, Shawn P.
AU - Werner, Linda J.
AU - Nolan, Sherry
AU - Hilliard, Bobby A.
PY - 1998/12
Y1 - 1998/12
N2 - From 1993 to 1995, approximately 10% of the clinically healthy northern elephant seals (Mirounga angustirostris) at The Marine Mammal Center in California exhibited a large unexplained increase in their white blood cell (WBC) count. In these animals, WBC counts ranged from 28,780 to 125,000/mm3, with a mean of 50,087/mm3. Significant correlations between the leukocytosis and weight gain and day of admittance were identified, but no correlation existed between leukocytosis and general state of health, sex, length of stay, or diet. Bone marrow contamination of blood samples, erroneous automated leukocyte counts, and leukogram changes consistent with subclinical inflammation were the major factors contributing to the elevated WBC counts in these apparently clinically healthy animals.
AB - From 1993 to 1995, approximately 10% of the clinically healthy northern elephant seals (Mirounga angustirostris) at The Marine Mammal Center in California exhibited a large unexplained increase in their white blood cell (WBC) count. In these animals, WBC counts ranged from 28,780 to 125,000/mm3, with a mean of 50,087/mm3. Significant correlations between the leukocytosis and weight gain and day of admittance were identified, but no correlation existed between leukocytosis and general state of health, sex, length of stay, or diet. Bone marrow contamination of blood samples, erroneous automated leukocyte counts, and leukogram changes consistent with subclinical inflammation were the major factors contributing to the elevated WBC counts in these apparently clinically healthy animals.
KW - Bone marrow contamination
KW - Extradural intravertebral vein
KW - Mirounga angustirostris
KW - Northern elephant seal
KW - Serial blood samples
KW - Spurious leukocytosis
UR - http://www.scopus.com/inward/record.url?scp=0032248462&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032248462&partnerID=8YFLogxK
M3 - Article
C2 - 10065848
AN - SCOPUS:0032248462
VL - 29
SP - 408
EP - 412
JO - Journal of Zoo and Wildlife Medicine
JF - Journal of Zoo and Wildlife Medicine
SN - 1042-7260
IS - 4
ER -