Cats – telomere to telomere and nose to tail

Research output: Contribution to journalShort surveypeer-review

Abstract

Feline genomic medicine can decode human variants of uncertain significance (VUSs). Telomere-to-telomere genome assemblies are feasible for all felid species, supporting genetic evolution and speciation studies. Their highly conserved genomic organization compared to humans suggests cats may also decipher the intergenic variation affecting the 3D chromosome structures influencing gene regulation.

Original languageEnglish (US)
Pages (from-to)865-867
Number of pages3
JournalTrends in Genetics
Volume37
Issue number10
DOIs
StatePublished - Oct 2021
Externally publishedYes

Keywords

  • felines
  • gapless assembly
  • genome editing
  • genome sequencing
  • phase-genome
  • precision medicine

ASJC Scopus subject areas

  • Genetics

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