Cats – telomere to telomere and nose to tail

Research output: Contribution to journalShort surveypeer-review


Feline genomic medicine can decode human variants of uncertain significance (VUSs). Telomere-to-telomere genome assemblies are feasible for all felid species, supporting genetic evolution and speciation studies. Their highly conserved genomic organization compared to humans suggests cats may also decipher the intergenic variation affecting the 3D chromosome structures influencing gene regulation.

Original languageEnglish (US)
Pages (from-to)865-867
Number of pages3
JournalTrends in Genetics
Issue number10
StatePublished - Oct 2021
Externally publishedYes


  • felines
  • gapless assembly
  • genome editing
  • genome sequencing
  • phase-genome
  • precision medicine

ASJC Scopus subject areas

  • Genetics


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