Catalytic C-H amination for the preparation of substituted 1,2-diamines

David Olson, J. Du Bois

Research output: Contribution to journalArticle

80 Scopus citations

Abstract

Rhodium-catalyzed C-H insertion of hydroxylamine-derived sulfamate esters makes possible the synthesis of unique oxathiadiazinane heterocycles, which upon mild reduction furnish differentially substituted 1,2-diamine products. This highly chemo- and diastereoselective transformation underscores the power of catalytic C-H functionalization as a general approach to C-N bond construction.

Original languageEnglish (US)
Pages (from-to)11248-11249
Number of pages2
JournalJournal of the American Chemical Society
Volume130
Issue number34
DOIs
StatePublished - Aug 27 2008
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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