Catalytic C-H amination for the preparation of substituted 1,2-diamines

David Olson, J. Du Bois

Research output: Contribution to journal › Article

78 Citations (Scopus)

Abstract

Rhodium-catalyzed C-H insertion of hydroxylamine-derived sulfamate esters makes possible the synthesis of unique oxathiadiazinane heterocycles, which upon mild reduction furnish differentially substituted 1,2-diamine products. This highly chemo- and diastereoselective transformation underscores the power of catalytic C-H functionalization as a general approach to C-N bond construction.

Original languageEnglish (US)
Pages (from-to)11248-11249
Number of pages2
JournalJournal of the American Chemical Society
Volume130
Issue number34
DOIs
StatePublished - Aug 27 2008
Externally publishedYes

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Amination
Rhodium
Hydroxylamine
Diamines
Esters
Preparation H
sulfamic acid

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Catalytic C-H amination for the preparation of substituted 1,2-diamines. / Olson, David; Du Bois, J.

In: Journal of the American Chemical Society, Vol. 130, No. 34, 27.08.2008, p. 11248-11249.

Research output: Contribution to journal › Article

Olson, D & Du Bois, J 2008, 'Catalytic C-H amination for the preparation of substituted 1,2-diamines', Journal of the American Chemical Society, vol. 130, no. 34, pp. 11248-11249. https://doi.org/10.1021/ja803344v
Olson D, Du Bois J. Catalytic C-H amination for the preparation of substituted 1,2-diamines. Journal of the American Chemical Society. 2008 Aug 27;130(34):11248-11249. https://doi.org/10.1021/ja803344v
Olson, David ; Du Bois, J. / Catalytic C-H amination for the preparation of substituted 1,2-diamines. In: Journal of the American Chemical Society. 2008 ; Vol. 130, No. 34. pp. 11248-11249.
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