Cat-scratch disease

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Cat-scratch disease (CSD) was first described by Debré in 1950, yet the causative bacterial agent of CSD remained obscure until 1992, when Bartonella (formerly Rochalimaea) henselae was implicated in CSD by serological and microbiologic studies. Bartonella henselae had initially been linked to bacillary angiomatosis (BA), a vascular proliferative disease most commonly associated with long-standing human immunodeficiency virus infection or other significant immunosuppression. Bartonella henselae has also been associated with bacillary peliosis, relapsing bacteraemia and endocarditis in humans. Cats are healthy carriers of B. henselae, and can be bacteraemic for months or years. Cat-to-cat transmission of the organism by the cat flea, with no direct contact transmission, has been demonstrated. Two new Bartonella species have been identified in the cat reservoir, namely: B. clarridgeiae and B. koehlerae. The role of these species in the aetiology of CSD still needs to be confirmed by isolation or DNA identification from lesions in humans. The author discusses the present state of knowledge on the aetiology, clinical features and epidemiological characteristics of CSD/BA, in addition to diagnosis, treatment and prevention.

Original languageEnglish (US)
Pages (from-to)136-150
Number of pages15
JournalOIE Revue Scientifique et Technique
Volume12
Issue number1
StatePublished - Apr 2000

Fingerprint

cat scratch disease
Cat-Scratch Disease
Bartonella henselae
Cats
Bacillary Angiomatosis
Bartonella
cats
Bartonella koehlerae
etiology
Bartonella clarridgeiae
Ctenocephalides
Ctenocephalides felis
endocarditis
bacteremia
Purpura
immunosuppression
HIV infections
Virus Diseases
direct contact
Bacteremia

Keywords

  • Bacillary angiomatosis
  • Bartonella clarridgeiae
  • Bartonella henselae
  • Cat-scratch disease
  • Cats
  • Zoonoses

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Cat-scratch disease. / Chomel, Bruno B.

In: OIE Revue Scientifique et Technique, Vol. 12, No. 1, 04.2000, p. 136-150.

Research output: Contribution to journalArticle

Chomel, Bruno B. / Cat-scratch disease. In: OIE Revue Scientifique et Technique. 2000 ; Vol. 12, No. 1. pp. 136-150.
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