Cardiovascular safety of rapid treatment with intramuscular haloperidol

P. T. Donlon, J. Hopkin, C. B. Schaffer, Ezra A Amsterdam

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The results of this study indicate a high degree of cardiovascular safety for healthy subjects who require treatment with moderate doses of haloperidol at 30 minute intervals for the control of the symptoms of acute psychosis. Nevertheless, it is prudent to assume that the risk of cardiovascular effects during rapid treatment with neuroleptics may be greater in elderly psychotic patients and all patients who are medically ill, particularly with cardiovascular disease. Patients in these categories should be treated with small doses of haloperidol and monitored closely throughout rapid treatment with neuroleptics. Idiosyncratic reaction to haloperidol and other neuroleptics is also a possibility for any patient.

Original languageEnglish (US)
Pages (from-to)233-234
Number of pages2
JournalAmerican Journal of Psychiatry
Issue number2
StatePublished - 1979

ASJC Scopus subject areas

  • Psychiatry and Mental health


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