Cardiac performance in conscious healthy dogs during dobutamine infusion

K. McEntee, C. Clercx, Bruno H Pypendop, D. Peeters, M. Balligand, V. D'Orio, M. Henroteaux

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The aim of this study was to determine the cardiac performance of conscious healthy dogs during stimulation with dobutamine. Eight healthy unsedated beagle dogs were used. Cardiac output was measured by the thermodilution technique and blood pressures by extravascular pressure transducers. Dobutamine challenge at a dosage ranging from 27.5 to 50 μg kg-1 min-1 induced a significant rise in cardiac power index (CPI), cardiac index (CI), stroke index (SI) and heart rate (HR) and a significant decrease in pulmonary vascular resistance (PVR) and systemic vascular resistance (SVR). The highest CPI was 2.05 times greater than its basal resting value. The CI was primarily responsible for this increase in CPI. The SI and HR contributed approximately 55 per cent and 45 per cent respectively of the maximal increase in CI.

Original languageEnglish (US)
Pages (from-to)234-239
Number of pages6
JournalResearch in Veterinary Science
Volume61
Issue number3
StatePublished - Nov 1996
Externally publishedYes

Fingerprint

Dobutamine
stroke
blood vessels
Vascular Resistance
heart rate
Heart Rate
Stroke
Dogs
Pressure Transducers
Thermodilution
dogs
cardiac output
Beagle
Cardiac Output
blood pressure
lungs
Blood Pressure
dosage
methodology

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

McEntee, K., Clercx, C., Pypendop, B. H., Peeters, D., Balligand, M., D'Orio, V., & Henroteaux, M. (1996). Cardiac performance in conscious healthy dogs during dobutamine infusion. Research in Veterinary Science, 61(3), 234-239.

Cardiac performance in conscious healthy dogs during dobutamine infusion. / McEntee, K.; Clercx, C.; Pypendop, Bruno H; Peeters, D.; Balligand, M.; D'Orio, V.; Henroteaux, M.

In: Research in Veterinary Science, Vol. 61, No. 3, 11.1996, p. 234-239.

Research output: Contribution to journalArticle

McEntee, K, Clercx, C, Pypendop, BH, Peeters, D, Balligand, M, D'Orio, V & Henroteaux, M 1996, 'Cardiac performance in conscious healthy dogs during dobutamine infusion', Research in Veterinary Science, vol. 61, no. 3, pp. 234-239.
McEntee K, Clercx C, Pypendop BH, Peeters D, Balligand M, D'Orio V et al. Cardiac performance in conscious healthy dogs during dobutamine infusion. Research in Veterinary Science. 1996 Nov;61(3):234-239.
McEntee, K. ; Clercx, C. ; Pypendop, Bruno H ; Peeters, D. ; Balligand, M. ; D'Orio, V. ; Henroteaux, M. / Cardiac performance in conscious healthy dogs during dobutamine infusion. In: Research in Veterinary Science. 1996 ; Vol. 61, No. 3. pp. 234-239.
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