Cardiac output, wedge pressure, and oxygen delivery

M. Mellema

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

The primary goal of the intensive care clinician can be said to be to optimize global Do2. This approach is the primary means by which the greatest killers of the critically ill patient (sepsis, SIRS, multiple organ dysfunction syndrome) may be addressed at present. Optimizing Do2 means delivering just enough to meet the patient's needs, because therapeutic measures taken to increase Do2 are all associated with some degree of risk. When used correctly, the PAC can allow the clinician to determine if Do2 is optimal and, if not, what steps might be best suited to improve on it. Newer generations of PACs are becoming available and can provide valuable additional insights into a patient's cardiovascular status. Nearly all attempts to increase Do2 address one or more of a relatively short list of variables. The specific endpoints of therapy need to be tailored to the individual patient but include clinical, metabolic, organ function, and hemodynamic markers. As clinicians expand our understanding of the key elements found in survivors of critical illness, it is hoped that this knowledge translates into better outcomes.

Original languageEnglish (US)
Pages (from-to)1175-1205
Number of pages31
JournalVeterinary Clinics of North America - Small Animal Practice
Volume31
Issue number6
StatePublished - 2001
Externally publishedYes

Fingerprint

Pulmonary Wedge Pressure
cardiac output
Cardiac Output
Oxygen
oxygen
Critical Illness
therapeutics
Multiple Organ Failure
Critical Care
hemodynamics
endpoints
Survivors
Sepsis
Hemodynamics
Therapeutics

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Cardiac output, wedge pressure, and oxygen delivery. / Mellema, M.

In: Veterinary Clinics of North America - Small Animal Practice, Vol. 31, No. 6, 2001, p. 1175-1205.

Research output: Contribution to journalArticle

@article{2f0f15f55be84b0b94e2ef636f875da0,
title = "Cardiac output, wedge pressure, and oxygen delivery",
abstract = "The primary goal of the intensive care clinician can be said to be to optimize global Do2. This approach is the primary means by which the greatest killers of the critically ill patient (sepsis, SIRS, multiple organ dysfunction syndrome) may be addressed at present. Optimizing Do2 means delivering just enough to meet the patient's needs, because therapeutic measures taken to increase Do2 are all associated with some degree of risk. When used correctly, the PAC can allow the clinician to determine if Do2 is optimal and, if not, what steps might be best suited to improve on it. Newer generations of PACs are becoming available and can provide valuable additional insights into a patient's cardiovascular status. Nearly all attempts to increase Do2 address one or more of a relatively short list of variables. The specific endpoints of therapy need to be tailored to the individual patient but include clinical, metabolic, organ function, and hemodynamic markers. As clinicians expand our understanding of the key elements found in survivors of critical illness, it is hoped that this knowledge translates into better outcomes.",
author = "M. Mellema",
year = "2001",
language = "English (US)",
volume = "31",
pages = "1175--1205",
journal = "Veterinary Clinics of North America - Small Animal Practice",
issn = "0195-5616",
publisher = "W.B. Saunders Ltd",
number = "6",

}

TY - JOUR

T1 - Cardiac output, wedge pressure, and oxygen delivery

AU - Mellema, M.

PY - 2001

Y1 - 2001

N2 - The primary goal of the intensive care clinician can be said to be to optimize global Do2. This approach is the primary means by which the greatest killers of the critically ill patient (sepsis, SIRS, multiple organ dysfunction syndrome) may be addressed at present. Optimizing Do2 means delivering just enough to meet the patient's needs, because therapeutic measures taken to increase Do2 are all associated with some degree of risk. When used correctly, the PAC can allow the clinician to determine if Do2 is optimal and, if not, what steps might be best suited to improve on it. Newer generations of PACs are becoming available and can provide valuable additional insights into a patient's cardiovascular status. Nearly all attempts to increase Do2 address one or more of a relatively short list of variables. The specific endpoints of therapy need to be tailored to the individual patient but include clinical, metabolic, organ function, and hemodynamic markers. As clinicians expand our understanding of the key elements found in survivors of critical illness, it is hoped that this knowledge translates into better outcomes.

AB - The primary goal of the intensive care clinician can be said to be to optimize global Do2. This approach is the primary means by which the greatest killers of the critically ill patient (sepsis, SIRS, multiple organ dysfunction syndrome) may be addressed at present. Optimizing Do2 means delivering just enough to meet the patient's needs, because therapeutic measures taken to increase Do2 are all associated with some degree of risk. When used correctly, the PAC can allow the clinician to determine if Do2 is optimal and, if not, what steps might be best suited to improve on it. Newer generations of PACs are becoming available and can provide valuable additional insights into a patient's cardiovascular status. Nearly all attempts to increase Do2 address one or more of a relatively short list of variables. The specific endpoints of therapy need to be tailored to the individual patient but include clinical, metabolic, organ function, and hemodynamic markers. As clinicians expand our understanding of the key elements found in survivors of critical illness, it is hoped that this knowledge translates into better outcomes.

UR - http://www.scopus.com/inward/record.url?scp=0035201501&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035201501&partnerID=8YFLogxK

M3 - Article

C2 - 11727333

AN - SCOPUS:0035201501

VL - 31

SP - 1175

EP - 1205

JO - Veterinary Clinics of North America - Small Animal Practice

JF - Veterinary Clinics of North America - Small Animal Practice

SN - 0195-5616

IS - 6

ER -