Abstract
Cardiac aging is a heterogeneous process caused by a combination of stochastic events which manifests as loss of structure and function in the heart, however several recent studies draw attention to aging being primarily a stem cell problem. This review summarizes findings in support of the "stem cell hypothesis of aging" and discusses the impact of age on cardiac stem cells and the niche. This article is part of a Special Issue entitled 'CV Aging'.
Original language | English (US) |
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Pages (from-to) | 32-36 |
Number of pages | 5 |
Journal | Journal of Molecular and Cellular Cardiology |
Volume | 83 |
DOIs | |
State | Published - Jun 1 2015 |
Externally published | Yes |
Keywords
- Aging
- Cardiac stem/progenitor cells
- Heart
ASJC Scopus subject areas
- Molecular Biology
- Cardiology and Cardiovascular Medicine