TY - JOUR
T1 - Cardiac activation mapping by MRI
AU - Knollmann, Friedrich D
AU - Mäurer, Jürgen
AU - Kücherer, Helmut
AU - Böck, Johannes C.
AU - O'Connell, J. William
AU - Botvinick, Elias
AU - Eichstädt, Hermann W.
AU - Felix, Roland
PY - 1996
Y1 - 1996
N2 - To establish cardiac MRI as a tool for noninvasive evaluation of activation patterns, 10 healthy volunteers were examined by cine segmented turboFLASH imaging sequences. Sequence modifications for low signal blood- pool appearance were applied, i.e., bilateral spatial saturation for segmented turboFLASH imaging. Pixelwise calculation of first-harmonic Fourier phase values (displayed as color-encoded maps) reveal either anterior septal or left ventricular free-wall sites as areas of earliest phase spreading towards posterior paraseptal sites in segmented turboFLASH scans. Phase scatter is lower in unsaturated than spatially presaturated segmented turboFLASH studies. Phase standard deviation in areas of endocardial displacement is higher in basal than apical slice positions in these scans. Early results indicate that first-harmonic Fourier phase analysis of cardiac- segmented turboFLASH MRI cine studies may provide a tool for noninvasive studies of cardiac activation sequence.
AB - To establish cardiac MRI as a tool for noninvasive evaluation of activation patterns, 10 healthy volunteers were examined by cine segmented turboFLASH imaging sequences. Sequence modifications for low signal blood- pool appearance were applied, i.e., bilateral spatial saturation for segmented turboFLASH imaging. Pixelwise calculation of first-harmonic Fourier phase values (displayed as color-encoded maps) reveal either anterior septal or left ventricular free-wall sites as areas of earliest phase spreading towards posterior paraseptal sites in segmented turboFLASH scans. Phase scatter is lower in unsaturated than spatially presaturated segmented turboFLASH studies. Phase standard deviation in areas of endocardial displacement is higher in basal than apical slice positions in these scans. Early results indicate that first-harmonic Fourier phase analysis of cardiac- segmented turboFLASH MRI cine studies may provide a tool for noninvasive studies of cardiac activation sequence.
KW - cardiac activation sequence
KW - Fourier phase analysis
KW - magnetic resonance imaging
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U2 - 10.1007/BF01759776
DO - 10.1007/BF01759776
M3 - Article
C2 - 8773998
AN - SCOPUS:0029973158
VL - 4
SP - 19
EP - 25
JO - Magnetic Resonance Materials in Physics, Biology, and Medicine
JF - Magnetic Resonance Materials in Physics, Biology, and Medicine
SN - 0968-5243
IS - 1
ER -