Carcinosarcoma (malignant mixed tumor) of the parotid: Report of a case with a pure rhabdomyosarcoma component

Regina F Gandour-Edwards, P. J. Donald, P. J. Vogt, R. Munn, K. W. Min

Research output: Contribution to journalArticle

34 Scopus citations


Background. Carcinosarcoma or true malignant mixed tumor of the parotid gland is extremely rare, accounting for <1% of all salivary gland malignancies. Methods. A 63-year-old woman presented with a 5-cm right parotid mass which was resected with a radical parotidectomy and infratemporal fossa dissection. Results. The tumor contained two distinctive histologic patterns, that of a poorly differentiated ductal carcinoma and a pleomorphic rhabdomyosarcoma. Additionally, a residual focus of pleomorphic adenoma was present peripherally. Immunohistochemical and electron microscopic studies confirmed the skeletal muscle differentiation. Conclusions. The pattern of combined rhabdomyosarcoma and ductal carcinoma has not been previously reported and adds further evidence to the myoepithelial derivation of these tumors.

Original languageEnglish (US)
Pages (from-to)379-382
Number of pages4
JournalHead and Neck
Issue number4
StatePublished - 1994


ASJC Scopus subject areas

  • Otorhinolaryngology

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