Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes

Jeremy R. Sanborn, Xi Chen, Yun Chiao Yao, Joshua A. Hammons, Ramya H. Tunuguntla, Yuliang Zhang, Christina C. Newcomb, Jennifer A. Soltis, James J. De Yoreo, Anthony Van Buuren, Atul N. Parikh, Aleksandr Noy

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Biological membranes provide a fascinating example of a separation system that is multifunctional, tunable, precise, and efficient. Biomimetic membranes, which mimic the architecture of cellular membranes, have the potential to deliver significant improvements in specificity and permeability. Here, a fully synthetic biomimetic membrane is reported that incorporates ultra-efficient 1.5 nm diameter carbon nanotube porin (CNTPs) channels in a block-copolymer matrix. It is demonstrated that CNTPs maintain high proton and water permeability in these membranes. CNTPs can also mimic the behavior of biological gap junctions by forming bridges between vesicular compartments that allow transport of small molecules.

Original languageEnglish (US)
Article number1803355
JournalAdvanced Materials
DOIs
StateAccepted/In press - Jan 1 2018
Externally publishedYes

Fingerprint

Biological membranes
Porins
Carbon Nanotubes
Block copolymers
Carbon nanotubes
Membranes
Biomimetics
Protons
Molecules
Water

Keywords

  • artificial membranes
  • carbon nanotube porins
  • carbon nanotubes
  • fast transport
  • polymersomes

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Sanborn, J. R., Chen, X., Yao, Y. C., Hammons, J. A., Tunuguntla, R. H., Zhang, Y., ... Noy, A. (Accepted/In press). Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes. Advanced Materials, [1803355]. https://doi.org/10.1002/adma.201803355

Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes. / Sanborn, Jeremy R.; Chen, Xi; Yao, Yun Chiao; Hammons, Joshua A.; Tunuguntla, Ramya H.; Zhang, Yuliang; Newcomb, Christina C.; Soltis, Jennifer A.; De Yoreo, James J.; Van Buuren, Anthony; Parikh, Atul N.; Noy, Aleksandr.

In: Advanced Materials, 01.01.2018.

Research output: Contribution to journalArticle

Sanborn, JR, Chen, X, Yao, YC, Hammons, JA, Tunuguntla, RH, Zhang, Y, Newcomb, CC, Soltis, JA, De Yoreo, JJ, Van Buuren, A, Parikh, AN & Noy, A 2018, 'Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes', Advanced Materials. https://doi.org/10.1002/adma.201803355
Sanborn, Jeremy R. ; Chen, Xi ; Yao, Yun Chiao ; Hammons, Joshua A. ; Tunuguntla, Ramya H. ; Zhang, Yuliang ; Newcomb, Christina C. ; Soltis, Jennifer A. ; De Yoreo, James J. ; Van Buuren, Anthony ; Parikh, Atul N. ; Noy, Aleksandr. / Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes. In: Advanced Materials. 2018.
@article{e0863c15078d4f36b70ee47b3a6af52d,
title = "Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes",
abstract = "Biological membranes provide a fascinating example of a separation system that is multifunctional, tunable, precise, and efficient. Biomimetic membranes, which mimic the architecture of cellular membranes, have the potential to deliver significant improvements in specificity and permeability. Here, a fully synthetic biomimetic membrane is reported that incorporates ultra-efficient 1.5 nm diameter carbon nanotube porin (CNTPs) channels in a block-copolymer matrix. It is demonstrated that CNTPs maintain high proton and water permeability in these membranes. CNTPs can also mimic the behavior of biological gap junctions by forming bridges between vesicular compartments that allow transport of small molecules.",
keywords = "artificial membranes, carbon nanotube porins, carbon nanotubes, fast transport, polymersomes",
author = "Sanborn, {Jeremy R.} and Xi Chen and Yao, {Yun Chiao} and Hammons, {Joshua A.} and Tunuguntla, {Ramya H.} and Yuliang Zhang and Newcomb, {Christina C.} and Soltis, {Jennifer A.} and {De Yoreo}, {James J.} and {Van Buuren}, Anthony and Parikh, {Atul N.} and Aleksandr Noy",
year = "2018",
month = "1",
day = "1",
doi = "10.1002/adma.201803355",
language = "English (US)",
journal = "Advanced Materials",
issn = "0935-9648",
publisher = "Wiley-VCH Verlag",

}

TY - JOUR

T1 - Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes

AU - Sanborn, Jeremy R.

AU - Chen, Xi

AU - Yao, Yun Chiao

AU - Hammons, Joshua A.

AU - Tunuguntla, Ramya H.

AU - Zhang, Yuliang

AU - Newcomb, Christina C.

AU - Soltis, Jennifer A.

AU - De Yoreo, James J.

AU - Van Buuren, Anthony

AU - Parikh, Atul N.

AU - Noy, Aleksandr

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Biological membranes provide a fascinating example of a separation system that is multifunctional, tunable, precise, and efficient. Biomimetic membranes, which mimic the architecture of cellular membranes, have the potential to deliver significant improvements in specificity and permeability. Here, a fully synthetic biomimetic membrane is reported that incorporates ultra-efficient 1.5 nm diameter carbon nanotube porin (CNTPs) channels in a block-copolymer matrix. It is demonstrated that CNTPs maintain high proton and water permeability in these membranes. CNTPs can also mimic the behavior of biological gap junctions by forming bridges between vesicular compartments that allow transport of small molecules.

AB - Biological membranes provide a fascinating example of a separation system that is multifunctional, tunable, precise, and efficient. Biomimetic membranes, which mimic the architecture of cellular membranes, have the potential to deliver significant improvements in specificity and permeability. Here, a fully synthetic biomimetic membrane is reported that incorporates ultra-efficient 1.5 nm diameter carbon nanotube porin (CNTPs) channels in a block-copolymer matrix. It is demonstrated that CNTPs maintain high proton and water permeability in these membranes. CNTPs can also mimic the behavior of biological gap junctions by forming bridges between vesicular compartments that allow transport of small molecules.

KW - artificial membranes

KW - carbon nanotube porins

KW - carbon nanotubes

KW - fast transport

KW - polymersomes

UR - http://www.scopus.com/inward/record.url?scp=85055684602&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85055684602&partnerID=8YFLogxK

U2 - 10.1002/adma.201803355

DO - 10.1002/adma.201803355

M3 - Article

C2 - 30368926

AN - SCOPUS:85055684602

JO - Advanced Materials

JF - Advanced Materials

SN - 0935-9648

M1 - 1803355

ER -