Canonical Microcircuits for Predictive Coding

Andre M. Bastos, William Martin Usrey, Rick A. Adams, George R Mangun, Pascal Fries, Karl J. Friston

Research output: Contribution to journalArticle

754 Scopus citations

Abstract

This Perspective considers the influential notion of a canonical (cortical) microcircuit in light of recent theories about neuronal processing. Specifically, we conciliate quantitative studies of microcircuitry and the functional logic of neuronal computations. We revisit the established idea that message passing among hierarchical cortical areas implements a form of Bayesian inference-paying careful attention to the implications for intrinsic connections among neuronal populations. By deriving canonical forms for these computations, one can associate specific neuronal populations with specific computational roles. This analysis discloses a remarkable correspondence between the microcircuitry of the cortical column and the connectivity implied by predictive coding. Furthermore, it provides some intuitive insights into the functional asymmetries between feedforward and feedback connections and the characteristic frequencies over which they operate.

Original languageEnglish (US)
Pages (from-to)695-711
Number of pages17
JournalNeuron
Volume76
Issue number4
DOIs
StatePublished - Nov 21 2012

ASJC Scopus subject areas

  • Neuroscience(all)

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    Bastos, A. M., Usrey, W. M., Adams, R. A., Mangun, G. R., Fries, P., & Friston, K. J. (2012). Canonical Microcircuits for Predictive Coding. Neuron, 76(4), 695-711. https://doi.org/10.1016/j.neuron.2012.10.038