Canine atopic dermatitis: A retrospective study of 169 cases examined at the University of California, Davis, 1992-1998. Part II. Response to hyposensitization

Gila Zur, Stephen D White, Peter J. Ihrke, Philip H Kass, Nina Toebe

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

One hundred and sixty-nine dogs were diagnosed with atopic dermatitis, and treated with hyposensitization for at least 1 year based on the results of either intradermal skin tests (IDST) or enzyme-linked immunosorbant serum assays (ELISA). Excellent (i.e. hyposensitization alone controlled clinical signs), good (> 50% improvement), moderate (< 50% improvement) and no (clinical signs were unchanged) responses were seen in 19.5, 32.5, 20.1 and 27.8%, respectively. Age of onset, age when treatment was initiated or the duration of clinical signs had no influence on response to hyposensitization. Dogs having concurrent flea allergy dermatitis were statistically more likely to respond better than dogs with concurrent food allergies. Although not statistically significant, there were trends for Golden Retriever and male dogs to respond better than other breeds and female dogs, respectively. Dogs having more than 21 positive reactions in allergy tests and treated with more than 21 allergens had lower response scores, and a longer time course before achieving beneficial response. Lower response scores were seen in dogs having positive reactions to cultivated plants, grasses, trees or insects. There was no difference in response to hyposensitization whether based on IDST or ELISA results.

Original languageEnglish (US)
Pages (from-to)103-111
Number of pages9
JournalVeterinary Dermatology
Volume13
Issue number2
DOIs
StatePublished - Apr 2002

Keywords

  • Atopic dermatitis
  • Dog
  • ELISA
  • Flea
  • Hyposensitization
  • Intradermal skin test

ASJC Scopus subject areas

  • veterinary(all)

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