Calculation of organ doses for a large number of patients undergoing CT examinations

Amir Bahadori, Diana L Miglioretti, Randell Kruger, Michael Flynn, Sheila Weinmann, Rebecca Smith-Bindman, Choonsik Lee

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

OBJECTIVE. The objective of our study was to develop an automated calculation method to provide organ dose assessment for a large cohort of pediatric and adult patients undergoing CT examinations. MATERIALS AND METHODS. We adopted two dose libraries that were previously published: the volume CT dose index-normalized organ dose library and the tube current-exposure time product (100 mAs)-normalized weighted CT dose index library. We developed an algorithm to calculate organ doses using the two dose libraries and the CT parameters available from DICOM data. We calculated organ doses for pediatric (n = 2499) and adult (n = 2043) CT examinations randomly selected from four health care systems in the United States and compared the adult organ doses with the values calculated from the ImPACT calculator. RESULTS. The median brain dose was 20 mGy (pediatric) and 24 mGy (adult), and the brain dose was greater than 40 mGy for 11% (pediatric) and 18% (adult) of the head CT studies. Both the National Cancer Institute (NCI) and ImPACT methods provided similar organ doses (median discrepancy <20%) for all organs except the organs located close to the scanning boundaries. The visual comparisons of scanning coverage and phantom anatomies revealed that the NCI method, which is based on realistic computational phantoms, provides more accurate organ doses than the ImPACT method. CONCLUSION. The automated organ dose calculation method developed in this study reduces the time needed to calculate doses for a large number of patients. We have successfully used this method for a variety of CT-related studies including retrospective epidemiologic studies and CT dose trend analysis studies.

Original languageEnglish (US)
Pages (from-to)827-833
Number of pages7
JournalAmerican Journal of Roentgenology
Volume205
Issue number4
DOIs
StatePublished - Oct 1 2015

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Libraries
Pediatrics
National Cancer Institute (U.S.)
Cone-Beam Computed Tomography
Brain
Epidemiologic Studies
Anatomy
Retrospective Studies
Head
Delivery of Health Care

Keywords

  • CT
  • Dosimetry
  • Informatics
  • Monte Carlo simulations

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Calculation of organ doses for a large number of patients undergoing CT examinations. / Bahadori, Amir; Miglioretti, Diana L; Kruger, Randell; Flynn, Michael; Weinmann, Sheila; Smith-Bindman, Rebecca; Lee, Choonsik.

In: American Journal of Roentgenology, Vol. 205, No. 4, 01.10.2015, p. 827-833.

Research output: Contribution to journalArticle

Bahadori, A, Miglioretti, DL, Kruger, R, Flynn, M, Weinmann, S, Smith-Bindman, R & Lee, C 2015, 'Calculation of organ doses for a large number of patients undergoing CT examinations', American Journal of Roentgenology, vol. 205, no. 4, pp. 827-833. https://doi.org/10.2214/AJR.14.14135
Bahadori, Amir ; Miglioretti, Diana L ; Kruger, Randell ; Flynn, Michael ; Weinmann, Sheila ; Smith-Bindman, Rebecca ; Lee, Choonsik. / Calculation of organ doses for a large number of patients undergoing CT examinations. In: American Journal of Roentgenology. 2015 ; Vol. 205, No. 4. pp. 827-833.
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