Calculation of body surface area via computed tomography-guided modeling in domestic rabbits (Oryctolagus cuniculus)

Ashley M. Zehnder, Michelle Hawkins, Earl A. Trestrail, Randall W. Holt, Michael S Kent

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective-To optimize the use of CT-guided modeling for the calculation of body surface area (BSA) in domestic rabbits (Oryctolagus cuniculus). Animals-12 domestic rabbits. Procedures-Adult rabbits (body weight, 1 to > 4 kg) that were client-owned animals undergoing CT for disease diagnosis or deceased laboratory animals donated from other research projects were scanned with a CT scanner. Images were transferred to a radiation therapy planning software program. Image slices were captured as contiguous slices at 100 kVp and 100 mA and processed to 0.1-cm-thick sections. The length of each contoured slice was summed to calculate a final BSA measurement. Nonlinear regression analysis was then used to derive an equation for the calculation of BSA in rabbits. Results-The constant calculated by use of this method was 9.9 (range, 9.59 to 10). The R2 for the goodness of fit was 0.9332. The equation that best described BSA as a function of body weight for domestic rabbits with this method was as follows: BSA = (9.9 X [body weight {in grams}]2/3)/10,000. Conclusions and Clinical Relevance-The BSA calculated via the CT-guided method yielded results similar to those obtained with equations for other similarly sized mammals and verified the use of such equations for rabbits. Additionally, this technique can be used for species that lack equations for the accurate calculation of BSA.

Original languageEnglish (US)
Pages (from-to)1859-1863
Number of pages5
JournalAmerican Journal of Veterinary Research
Volume73
Issue number12
DOIs
StatePublished - Dec 2012

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Oryctolagus cuniculus
Body Surface Area
computed tomography
surface area
rabbits
Tomography
Rabbits
Body Weight
body weight
scanners
Laboratory Animals
radiotherapy
disease diagnosis
research projects
methodology
laboratory animals
Mammals
animals
regression analysis
Radiotherapy

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Calculation of body surface area via computed tomography-guided modeling in domestic rabbits (Oryctolagus cuniculus). / Zehnder, Ashley M.; Hawkins, Michelle; Trestrail, Earl A.; Holt, Randall W.; Kent, Michael S.

In: American Journal of Veterinary Research, Vol. 73, No. 12, 12.2012, p. 1859-1863.

Research output: Contribution to journalArticle

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