Abstract
This study represents the first reported in a series designed to define the role of calcium in the pathophysiology of shock. The authors have demonstrated a decrease in the concentration of extracellular calcium in hemorrhagic shock in baboons. This is aggravated by a calcium free resuscitation. The authors also have demonstrated that there is an increase in extracellular concentration of magnesium during the shock period; however, this is minimized by a calcium free resuscitation after 2 1/2 hours. The authors conclude, at the present time, that calcium should be present in resuscitation fluids and that supplemental calcium should be given when massive transfusions are necessary.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 633-638 |
| Number of pages | 6 |
| Journal | Journal of Trauma |
| Volume | 16 |
| Issue number | 8 |
| State | Published - 1976 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Surgery
Cite this
Calcium flux during hemorrhagic shock in baboons. / Trunkey, D.; Holcroft, James W; Carpenter, M. A.
In: Journal of Trauma, Vol. 16, No. 8, 1976, p. 633-638.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Calcium flux during hemorrhagic shock in baboons
AU - Trunkey, D.
AU - Holcroft, James W
AU - Carpenter, M. A.
PY - 1976
Y1 - 1976
N2 - This study represents the first reported in a series designed to define the role of calcium in the pathophysiology of shock. The authors have demonstrated a decrease in the concentration of extracellular calcium in hemorrhagic shock in baboons. This is aggravated by a calcium free resuscitation. The authors also have demonstrated that there is an increase in extracellular concentration of magnesium during the shock period; however, this is minimized by a calcium free resuscitation after 2 1/2 hours. The authors conclude, at the present time, that calcium should be present in resuscitation fluids and that supplemental calcium should be given when massive transfusions are necessary.
AB - This study represents the first reported in a series designed to define the role of calcium in the pathophysiology of shock. The authors have demonstrated a decrease in the concentration of extracellular calcium in hemorrhagic shock in baboons. This is aggravated by a calcium free resuscitation. The authors also have demonstrated that there is an increase in extracellular concentration of magnesium during the shock period; however, this is minimized by a calcium free resuscitation after 2 1/2 hours. The authors conclude, at the present time, that calcium should be present in resuscitation fluids and that supplemental calcium should be given when massive transfusions are necessary.
UR - http://www.scopus.com/inward/record.url?scp=0017096802&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017096802&partnerID=8YFLogxK
M3 - Article
C2 - 183002
AN - SCOPUS:0017096802
VL - 16
SP - 633
EP - 638
JO - Journal of Trauma and Acute Care Surgery
JF - Journal of Trauma and Acute Care Surgery
SN - 2163-0755
IS - 8
ER -