Abstract
Differentiated neuroblastoma cells (clone N18TG2-A1) were investigated by means of intracellular dialysis technique. A slow component of the potential-dependent inward current was observed in these cells. Changes in current amplitude produced by changes in the ionic composition of intra- and extracellular media showed that this component is carried by calcium ions. The calcium inward current was observed in all investigated cells. It could be activated by membrane depolarization to the level of -70 - -65 mV and reached maximum amplitude at -30 - -40 mV. Kinetic parameters of this current were studied. A conclusion is made that calcium current in differentiated neuroblastoma cells is similar to the fast component of the calcium current in normal neurons of rat dorsal root ganglion.
| Original language | Undefined/Unknown |
|---|---|
| Pages (from-to) | 527-531 |
| Number of pages | 5 |
| Journal | Neirofiziologiya |
| Volume | 16 |
| Issue number | 4 |
| State | Published - 1984 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Physiology
Cite this
Kal'tsievye toki differentsirovannykh kletok neǐroblastomy myshi. / Veselovskiǐ, N. S.; Pogorelaia, N. K.; Fomina, Alla F.
In: Neirofiziologiya, Vol. 16, No. 4, 1984, p. 527-531.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Kal'tsievye toki differentsirovannykh kletok neǐroblastomy myshi.
AU - Veselovskiǐ, N. S.
AU - Pogorelaia, N. K.
AU - Fomina, Alla F
PY - 1984
Y1 - 1984
N2 - Differentiated neuroblastoma cells (clone N18TG2-A1) were investigated by means of intracellular dialysis technique. A slow component of the potential-dependent inward current was observed in these cells. Changes in current amplitude produced by changes in the ionic composition of intra- and extracellular media showed that this component is carried by calcium ions. The calcium inward current was observed in all investigated cells. It could be activated by membrane depolarization to the level of -70 - -65 mV and reached maximum amplitude at -30 - -40 mV. Kinetic parameters of this current were studied. A conclusion is made that calcium current in differentiated neuroblastoma cells is similar to the fast component of the calcium current in normal neurons of rat dorsal root ganglion.
AB - Differentiated neuroblastoma cells (clone N18TG2-A1) were investigated by means of intracellular dialysis technique. A slow component of the potential-dependent inward current was observed in these cells. Changes in current amplitude produced by changes in the ionic composition of intra- and extracellular media showed that this component is carried by calcium ions. The calcium inward current was observed in all investigated cells. It could be activated by membrane depolarization to the level of -70 - -65 mV and reached maximum amplitude at -30 - -40 mV. Kinetic parameters of this current were studied. A conclusion is made that calcium current in differentiated neuroblastoma cells is similar to the fast component of the calcium current in normal neurons of rat dorsal root ganglion.
UR - http://www.scopus.com/inward/record.url?scp=0021196375&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021196375&partnerID=8YFLogxK
M3 - Article
C2 - 6092979
AN - SCOPUS:0021196375
VL - 16
SP - 527
EP - 531
JO - Neirofiziologiya
JF - Neirofiziologiya
SN - 0028-2561
IS - 4
ER -