C 60 nanoparticle quenching used as a biological label

Jun Feng, Sally Mack, Guomin Shan, Shirley Gee, Bruce D. Hammock, Ian M. Kennedy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Carbon 60 has been used in a functionalized form in a bioassay for a common herbicide, atrazine. It was found that the C 60 is a very effective quencher of fluorescence from number of common dyes. C 60 was conjugated to atrazine for use in an immunoassay in which fluorescence from rhodamine was measured. Quenching of the rhodamine emission provided a detection scheme in this assay that yielded very good limit of detection. The C 60 quenching scheme can be used with a wide variety of fluorescent dyes, permitting the potential use of a range of small, cheap excitation sources.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsA.P. Savitsky, D.J. Bornhop, R. Raghachari, S.I. Achilefu
Pages156-163
Number of pages8
Volume4967
DOIs
StatePublished - 2003
EventPROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Genetically Engineered and Optical Probes for Biomedical Applications - San Jose, CA, United States
Duration: Jan 27 2003Jan 28 2003

Other

OtherPROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Genetically Engineered and Optical Probes for Biomedical Applications
CountryUnited States
CitySan Jose, CA
Period1/27/031/28/03

Keywords

  • Atrazine
  • Carbon
  • Fluorescence
  • Fullerene
  • Immunoassay
  • Quenching

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

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  • Cite this

    Feng, J., Mack, S., Shan, G., Gee, S., Hammock, B. D., & Kennedy, I. M. (2003). C 60 nanoparticle quenching used as a biological label In A. P. Savitsky, D. J. Bornhop, R. Raghachari, & S. I. Achilefu (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4967, pp. 156-163) https://doi.org/10.1117/12.478397