Burn-Induced Coagulopathies: a Comprehensive Review

Robert L. Ball, John W. Keyloun, Kathleen Brummel-Ziedins, Thomas Orfeo, Tina L. Palmieri, Laura S. Johnson, Lauren T. Moffatt, Anthony E. Pusateri, Jeffrey W. Shupp

Research output: Contribution to journalArticle

Abstract

Burn-induced coagulopathy is not well understood, and consensus on diagnosis, prevention, and treatments are lacking. In this review, literature on burn-induced (and associated) coagulopathy is presented along with the current understanding of the effects of burn injury on the interactions among coagulation, fibrinolysis, and inflammation in the acute resuscitative phase and reconstructive phase of care. The role of conventional tests of coagulopathy and functional assays like thromboelastography or thromboelastometry will also be discussed. Finally, reported methods for the prevention and treatment of complications related to burn-induced coagulopathy will be reviewed.

Original languageEnglish (US)
Pages (from-to)154-167
Number of pages14
JournalShock (Augusta, Ga.)
Volume54
Issue number2
DOIs
StatePublished - Aug 1 2020

ASJC Scopus subject areas

  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

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  • Cite this

    Ball, R. L., Keyloun, J. W., Brummel-Ziedins, K., Orfeo, T., Palmieri, T. L., Johnson, L. S., Moffatt, L. T., Pusateri, A. E., & Shupp, J. W. (2020). Burn-Induced Coagulopathies: a Comprehensive Review. Shock (Augusta, Ga.), 54(2), 154-167. https://doi.org/10.1097/SHK.0000000000001484