Abstract
Background: Bronchiectasis is a permanent and debilitating sequel to chronic or severe airway injury, however, diseases associated with this condition are poorly defined. Objective: To evaluate results of diagnostic tests used to document bronchiectasis and to characterize underlying or concurrent disease processes. Animals: Eighty-six dogs that had bronchoscopy performed and a diagnosis of bronchiectasis. Methods: Retrospective case series. Radiographs, computed tomography, and bronchoscopic findings were evaluated for features of bronchiectasis. Clinical diagnoses of pneumonia (aspiration, interstitial, foreign body, other), eosinophilic bronchopneumopathy (EBP), and inflammatory airway disease (IAD) were made based on results of history, physical examination, and diagnostic testing, including bronchoalveolar lavage fluid analysis and microbiology. Results: Bronchiectasis was diagnosed in 14% of dogs (86/621) that had bronchoscopy performed. Dogs ranged in age from 0.5 to 14 years with duration of signs from 3 days to 10 years. Bronchiectasis was documented during bronchoscopy in 79/86 dogs (92%), thoracic radiology in 50/83 dogs (60%), and CT in 34/34 dogs (100%). Concurrent airway collapse was detected during bronchoscopy in 50/86 dogs (58%), and focal or multifocal mucus plugging of segmental or subsegmental bronchi was found in 41/86 dogs (48%). Final diagnoses included pneumonia (45/86 dogs, 52%), EBP (10/86 dogs, 12%) and IAD (31/86 dogs, 36%). Bacteria were isolated in 24/86 cases (28%), with Streptococcus spp, Pasteurella spp, enteric organisms, and Stenotrophomonas isolated most frequently. Conclusions and Clinical Importance: Bronchiectasis can be anticipated in dogs with infectious or inflammatory respiratory disease. Advanced imaging and bronchoscopy are useful in making the diagnosis and identifying concurrent respiratory disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 247-254 |
| Number of pages | 8 |
| Journal | Journal of Veterinary Internal Medicine |
| Volume | 30 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2016 |
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Keywords
- COPD
- Bacterial
- Computed tomography
- Endoscopy
- Microbiology
- Parenchymal disease
- Pneumonia
- Pulmonary infiltrates with eosinophilia
- Radiology and diagnostic imaging
- Respiratory tract
ASJC Scopus subject areas
- veterinary(all)
Cite this
Bronchoscopy, Imaging, and Concurrent Diseases in Dogs with Bronchiectasis : (2003-2014). / Johnson, Lynelle R; Johnson, Eric G; Vernau, William; Kass, Philip H; Byrne, Barbara A.
In: Journal of Veterinary Internal Medicine, Vol. 30, No. 1, 01.01.2016, p. 247-254.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bronchoscopy, Imaging, and Concurrent Diseases in Dogs with Bronchiectasis
T2 - (2003-2014)
AU - Johnson, Lynelle R
AU - Johnson, Eric G
AU - Vernau, William
AU - Kass, Philip H
AU - Byrne, Barbara A
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Background: Bronchiectasis is a permanent and debilitating sequel to chronic or severe airway injury, however, diseases associated with this condition are poorly defined. Objective: To evaluate results of diagnostic tests used to document bronchiectasis and to characterize underlying or concurrent disease processes. Animals: Eighty-six dogs that had bronchoscopy performed and a diagnosis of bronchiectasis. Methods: Retrospective case series. Radiographs, computed tomography, and bronchoscopic findings were evaluated for features of bronchiectasis. Clinical diagnoses of pneumonia (aspiration, interstitial, foreign body, other), eosinophilic bronchopneumopathy (EBP), and inflammatory airway disease (IAD) were made based on results of history, physical examination, and diagnostic testing, including bronchoalveolar lavage fluid analysis and microbiology. Results: Bronchiectasis was diagnosed in 14% of dogs (86/621) that had bronchoscopy performed. Dogs ranged in age from 0.5 to 14 years with duration of signs from 3 days to 10 years. Bronchiectasis was documented during bronchoscopy in 79/86 dogs (92%), thoracic radiology in 50/83 dogs (60%), and CT in 34/34 dogs (100%). Concurrent airway collapse was detected during bronchoscopy in 50/86 dogs (58%), and focal or multifocal mucus plugging of segmental or subsegmental bronchi was found in 41/86 dogs (48%). Final diagnoses included pneumonia (45/86 dogs, 52%), EBP (10/86 dogs, 12%) and IAD (31/86 dogs, 36%). Bacteria were isolated in 24/86 cases (28%), with Streptococcus spp, Pasteurella spp, enteric organisms, and Stenotrophomonas isolated most frequently. Conclusions and Clinical Importance: Bronchiectasis can be anticipated in dogs with infectious or inflammatory respiratory disease. Advanced imaging and bronchoscopy are useful in making the diagnosis and identifying concurrent respiratory disease.
AB - Background: Bronchiectasis is a permanent and debilitating sequel to chronic or severe airway injury, however, diseases associated with this condition are poorly defined. Objective: To evaluate results of diagnostic tests used to document bronchiectasis and to characterize underlying or concurrent disease processes. Animals: Eighty-six dogs that had bronchoscopy performed and a diagnosis of bronchiectasis. Methods: Retrospective case series. Radiographs, computed tomography, and bronchoscopic findings were evaluated for features of bronchiectasis. Clinical diagnoses of pneumonia (aspiration, interstitial, foreign body, other), eosinophilic bronchopneumopathy (EBP), and inflammatory airway disease (IAD) were made based on results of history, physical examination, and diagnostic testing, including bronchoalveolar lavage fluid analysis and microbiology. Results: Bronchiectasis was diagnosed in 14% of dogs (86/621) that had bronchoscopy performed. Dogs ranged in age from 0.5 to 14 years with duration of signs from 3 days to 10 years. Bronchiectasis was documented during bronchoscopy in 79/86 dogs (92%), thoracic radiology in 50/83 dogs (60%), and CT in 34/34 dogs (100%). Concurrent airway collapse was detected during bronchoscopy in 50/86 dogs (58%), and focal or multifocal mucus plugging of segmental or subsegmental bronchi was found in 41/86 dogs (48%). Final diagnoses included pneumonia (45/86 dogs, 52%), EBP (10/86 dogs, 12%) and IAD (31/86 dogs, 36%). Bacteria were isolated in 24/86 cases (28%), with Streptococcus spp, Pasteurella spp, enteric organisms, and Stenotrophomonas isolated most frequently. Conclusions and Clinical Importance: Bronchiectasis can be anticipated in dogs with infectious or inflammatory respiratory disease. Advanced imaging and bronchoscopy are useful in making the diagnosis and identifying concurrent respiratory disease.
KW - COPD
KW - Bacterial
KW - Computed tomography
KW - Endoscopy
KW - Microbiology
KW - Parenchymal disease
KW - Pneumonia
KW - Pulmonary infiltrates with eosinophilia
KW - Radiology and diagnostic imaging
KW - Respiratory tract
UR - http://www.scopus.com/inward/record.url?scp=84956609627&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84956609627&partnerID=8YFLogxK
U2 - 10.1111/jvim.13809
DO - 10.1111/jvim.13809
M3 - Article
C2 - 26682874
AN - SCOPUS:84956609627
VL - 30
SP - 247
EP - 254
JO - Journal of Veterinary Internal Medicine
JF - Journal of Veterinary Internal Medicine
SN - 0891-6640
IS - 1
ER -