Bronchoscopy, Imaging, and Concurrent Diseases in Dogs with Bronchiectasis: (2003-2014)

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Abstract

Background: Bronchiectasis is a permanent and debilitating sequel to chronic or severe airway injury, however, diseases associated with this condition are poorly defined. Objective: To evaluate results of diagnostic tests used to document bronchiectasis and to characterize underlying or concurrent disease processes. Animals: Eighty-six dogs that had bronchoscopy performed and a diagnosis of bronchiectasis. Methods: Retrospective case series. Radiographs, computed tomography, and bronchoscopic findings were evaluated for features of bronchiectasis. Clinical diagnoses of pneumonia (aspiration, interstitial, foreign body, other), eosinophilic bronchopneumopathy (EBP), and inflammatory airway disease (IAD) were made based on results of history, physical examination, and diagnostic testing, including bronchoalveolar lavage fluid analysis and microbiology. Results: Bronchiectasis was diagnosed in 14% of dogs (86/621) that had bronchoscopy performed. Dogs ranged in age from 0.5 to 14 years with duration of signs from 3 days to 10 years. Bronchiectasis was documented during bronchoscopy in 79/86 dogs (92%), thoracic radiology in 50/83 dogs (60%), and CT in 34/34 dogs (100%). Concurrent airway collapse was detected during bronchoscopy in 50/86 dogs (58%), and focal or multifocal mucus plugging of segmental or subsegmental bronchi was found in 41/86 dogs (48%). Final diagnoses included pneumonia (45/86 dogs, 52%), EBP (10/86 dogs, 12%) and IAD (31/86 dogs, 36%). Bacteria were isolated in 24/86 cases (28%), with Streptococcus spp, Pasteurella spp, enteric organisms, and Stenotrophomonas isolated most frequently. Conclusions and Clinical Importance: Bronchiectasis can be anticipated in dogs with infectious or inflammatory respiratory disease. Advanced imaging and bronchoscopy are useful in making the diagnosis and identifying concurrent respiratory disease.

Original languageEnglish (US)
Pages (from-to)247-254
Number of pages8
JournalJournal of Veterinary Internal Medicine
Volume30
Issue number1
DOIs
StatePublished - Jan 1 2016

Fingerprint

bronchoscopy
Dog Diseases
Bronchiectasis
dog diseases
Bronchoscopy
image analysis
Dogs
dogs
respiratory tract diseases
pneumonia
Stenotrophomonas
Pasteurella
Aspiration Pneumonia
bronchi
radiology
foreign bodies
Interstitial Lung Diseases
Streptococcus
Bronchoalveolar Lavage Fluid
chest

Keywords

  • COPD
  • Bacterial
  • Computed tomography
  • Endoscopy
  • Microbiology
  • Parenchymal disease
  • Pneumonia
  • Pulmonary infiltrates with eosinophilia
  • Radiology and diagnostic imaging
  • Respiratory tract

ASJC Scopus subject areas

  • veterinary(all)

Cite this

@article{37ba4515ec3347c5975530c68f584aa1,
title = "Bronchoscopy, Imaging, and Concurrent Diseases in Dogs with Bronchiectasis: (2003-2014)",
abstract = "Background: Bronchiectasis is a permanent and debilitating sequel to chronic or severe airway injury, however, diseases associated with this condition are poorly defined. Objective: To evaluate results of diagnostic tests used to document bronchiectasis and to characterize underlying or concurrent disease processes. Animals: Eighty-six dogs that had bronchoscopy performed and a diagnosis of bronchiectasis. Methods: Retrospective case series. Radiographs, computed tomography, and bronchoscopic findings were evaluated for features of bronchiectasis. Clinical diagnoses of pneumonia (aspiration, interstitial, foreign body, other), eosinophilic bronchopneumopathy (EBP), and inflammatory airway disease (IAD) were made based on results of history, physical examination, and diagnostic testing, including bronchoalveolar lavage fluid analysis and microbiology. Results: Bronchiectasis was diagnosed in 14{\%} of dogs (86/621) that had bronchoscopy performed. Dogs ranged in age from 0.5 to 14 years with duration of signs from 3 days to 10 years. Bronchiectasis was documented during bronchoscopy in 79/86 dogs (92{\%}), thoracic radiology in 50/83 dogs (60{\%}), and CT in 34/34 dogs (100{\%}). Concurrent airway collapse was detected during bronchoscopy in 50/86 dogs (58{\%}), and focal or multifocal mucus plugging of segmental or subsegmental bronchi was found in 41/86 dogs (48{\%}). Final diagnoses included pneumonia (45/86 dogs, 52{\%}), EBP (10/86 dogs, 12{\%}) and IAD (31/86 dogs, 36{\%}). Bacteria were isolated in 24/86 cases (28{\%}), with Streptococcus spp, Pasteurella spp, enteric organisms, and Stenotrophomonas isolated most frequently. Conclusions and Clinical Importance: Bronchiectasis can be anticipated in dogs with infectious or inflammatory respiratory disease. Advanced imaging and bronchoscopy are useful in making the diagnosis and identifying concurrent respiratory disease.",
keywords = "COPD, Bacterial, Computed tomography, Endoscopy, Microbiology, Parenchymal disease, Pneumonia, Pulmonary infiltrates with eosinophilia, Radiology and diagnostic imaging, Respiratory tract",
author = "Johnson, {Lynelle R} and Johnson, {Eric G} and William Vernau and Kass, {Philip H} and Byrne, {Barbara A}",
year = "2016",
month = "1",
day = "1",
doi = "10.1111/jvim.13809",
language = "English (US)",
volume = "30",
pages = "247--254",
journal = "Journal of Veterinary Internal Medicine",
issn = "0891-6640",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Bronchoscopy, Imaging, and Concurrent Diseases in Dogs with Bronchiectasis

T2 - (2003-2014)

AU - Johnson, Lynelle R

AU - Johnson, Eric G

AU - Vernau, William

AU - Kass, Philip H

AU - Byrne, Barbara A

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Background: Bronchiectasis is a permanent and debilitating sequel to chronic or severe airway injury, however, diseases associated with this condition are poorly defined. Objective: To evaluate results of diagnostic tests used to document bronchiectasis and to characterize underlying or concurrent disease processes. Animals: Eighty-six dogs that had bronchoscopy performed and a diagnosis of bronchiectasis. Methods: Retrospective case series. Radiographs, computed tomography, and bronchoscopic findings were evaluated for features of bronchiectasis. Clinical diagnoses of pneumonia (aspiration, interstitial, foreign body, other), eosinophilic bronchopneumopathy (EBP), and inflammatory airway disease (IAD) were made based on results of history, physical examination, and diagnostic testing, including bronchoalveolar lavage fluid analysis and microbiology. Results: Bronchiectasis was diagnosed in 14% of dogs (86/621) that had bronchoscopy performed. Dogs ranged in age from 0.5 to 14 years with duration of signs from 3 days to 10 years. Bronchiectasis was documented during bronchoscopy in 79/86 dogs (92%), thoracic radiology in 50/83 dogs (60%), and CT in 34/34 dogs (100%). Concurrent airway collapse was detected during bronchoscopy in 50/86 dogs (58%), and focal or multifocal mucus plugging of segmental or subsegmental bronchi was found in 41/86 dogs (48%). Final diagnoses included pneumonia (45/86 dogs, 52%), EBP (10/86 dogs, 12%) and IAD (31/86 dogs, 36%). Bacteria were isolated in 24/86 cases (28%), with Streptococcus spp, Pasteurella spp, enteric organisms, and Stenotrophomonas isolated most frequently. Conclusions and Clinical Importance: Bronchiectasis can be anticipated in dogs with infectious or inflammatory respiratory disease. Advanced imaging and bronchoscopy are useful in making the diagnosis and identifying concurrent respiratory disease.

AB - Background: Bronchiectasis is a permanent and debilitating sequel to chronic or severe airway injury, however, diseases associated with this condition are poorly defined. Objective: To evaluate results of diagnostic tests used to document bronchiectasis and to characterize underlying or concurrent disease processes. Animals: Eighty-six dogs that had bronchoscopy performed and a diagnosis of bronchiectasis. Methods: Retrospective case series. Radiographs, computed tomography, and bronchoscopic findings were evaluated for features of bronchiectasis. Clinical diagnoses of pneumonia (aspiration, interstitial, foreign body, other), eosinophilic bronchopneumopathy (EBP), and inflammatory airway disease (IAD) were made based on results of history, physical examination, and diagnostic testing, including bronchoalveolar lavage fluid analysis and microbiology. Results: Bronchiectasis was diagnosed in 14% of dogs (86/621) that had bronchoscopy performed. Dogs ranged in age from 0.5 to 14 years with duration of signs from 3 days to 10 years. Bronchiectasis was documented during bronchoscopy in 79/86 dogs (92%), thoracic radiology in 50/83 dogs (60%), and CT in 34/34 dogs (100%). Concurrent airway collapse was detected during bronchoscopy in 50/86 dogs (58%), and focal or multifocal mucus plugging of segmental or subsegmental bronchi was found in 41/86 dogs (48%). Final diagnoses included pneumonia (45/86 dogs, 52%), EBP (10/86 dogs, 12%) and IAD (31/86 dogs, 36%). Bacteria were isolated in 24/86 cases (28%), with Streptococcus spp, Pasteurella spp, enteric organisms, and Stenotrophomonas isolated most frequently. Conclusions and Clinical Importance: Bronchiectasis can be anticipated in dogs with infectious or inflammatory respiratory disease. Advanced imaging and bronchoscopy are useful in making the diagnosis and identifying concurrent respiratory disease.

KW - COPD

KW - Bacterial

KW - Computed tomography

KW - Endoscopy

KW - Microbiology

KW - Parenchymal disease

KW - Pneumonia

KW - Pulmonary infiltrates with eosinophilia

KW - Radiology and diagnostic imaging

KW - Respiratory tract

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DO - 10.1111/jvim.13809

M3 - Article

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VL - 30

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