TY - JOUR
T1 - Bronchiectasis
T2 - Sex and gender considerations
AU - Morrissey, Brian M
AU - Harper, Richart W
PY - 2004/6
Y1 - 2004/6
N2 - Bronchiectasis in women may act more virulently. Identified gender and sex differences range from increased exposure risks to altered inflammatory responses. Common among the most well-documented examples is a differential immune response. There is sufficient evidence to suggest that chronic airway infection, most notably non-CF bronchiectasis, is a more common and more virulent disease in women. This is particularly evident in CF- and non-HIV-related environmental mycobacterial respiratory tract infections. Whether this represents an inflammatory-immune process, or environmental, anatomic, or other genetic difference remains to be detailed fully.
AB - Bronchiectasis in women may act more virulently. Identified gender and sex differences range from increased exposure risks to altered inflammatory responses. Common among the most well-documented examples is a differential immune response. There is sufficient evidence to suggest that chronic airway infection, most notably non-CF bronchiectasis, is a more common and more virulent disease in women. This is particularly evident in CF- and non-HIV-related environmental mycobacterial respiratory tract infections. Whether this represents an inflammatory-immune process, or environmental, anatomic, or other genetic difference remains to be detailed fully.
UR - http://www.scopus.com/inward/record.url?scp=1942476127&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1942476127&partnerID=8YFLogxK
U2 - 10.1016/j.ccm.2004.01.011
DO - 10.1016/j.ccm.2004.01.011
M3 - Article
C2 - 15099895
AN - SCOPUS:1942476127
VL - 25
SP - 361
EP - 372
JO - Clinics in Chest Medicine
JF - Clinics in Chest Medicine
SN - 0272-5231
IS - 2
ER -