Abstract
Bronchiectasis in women may act more virulently. Identified gender and sex differences range from increased exposure risks to altered inflammatory responses. Common among the most well-documented examples is a differential immune response. There is sufficient evidence to suggest that chronic airway infection, most notably non-CF bronchiectasis, is a more common and more virulent disease in women. This is particularly evident in CF- and non-HIV-related environmental mycobacterial respiratory tract infections. Whether this represents an inflammatory-immune process, or environmental, anatomic, or other genetic difference remains to be detailed fully.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 361-372 |
| Number of pages | 12 |
| Journal | Clinics in Chest Medicine |
| Volume | 25 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 2004 |
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ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Bronchiectasis : Sex and gender considerations. / Morrissey, Brian M; Harper, Richart W.
In: Clinics in Chest Medicine, Vol. 25, No. 2, 06.2004, p. 361-372.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bronchiectasis
T2 - Sex and gender considerations
AU - Morrissey, Brian M
AU - Harper, Richart W
PY - 2004/6
Y1 - 2004/6
N2 - Bronchiectasis in women may act more virulently. Identified gender and sex differences range from increased exposure risks to altered inflammatory responses. Common among the most well-documented examples is a differential immune response. There is sufficient evidence to suggest that chronic airway infection, most notably non-CF bronchiectasis, is a more common and more virulent disease in women. This is particularly evident in CF- and non-HIV-related environmental mycobacterial respiratory tract infections. Whether this represents an inflammatory-immune process, or environmental, anatomic, or other genetic difference remains to be detailed fully.
AB - Bronchiectasis in women may act more virulently. Identified gender and sex differences range from increased exposure risks to altered inflammatory responses. Common among the most well-documented examples is a differential immune response. There is sufficient evidence to suggest that chronic airway infection, most notably non-CF bronchiectasis, is a more common and more virulent disease in women. This is particularly evident in CF- and non-HIV-related environmental mycobacterial respiratory tract infections. Whether this represents an inflammatory-immune process, or environmental, anatomic, or other genetic difference remains to be detailed fully.
UR - http://www.scopus.com/inward/record.url?scp=1942476127&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1942476127&partnerID=8YFLogxK
U2 - 10.1016/j.ccm.2004.01.011
DO - 10.1016/j.ccm.2004.01.011
M3 - Article
C2 - 15099895
AN - SCOPUS:1942476127
VL - 25
SP - 361
EP - 372
JO - Clinics in Chest Medicine
JF - Clinics in Chest Medicine
SN - 0272-5231
IS - 2
ER -