Breaking the central dogma by RNA editing

Olena Maydanovych, Peter A. Beal

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

This review covers the advances in the understanding of the structure, mechanism, regulation, and biological functions of the ADAR (adenosine deaminases that act on ribonucleic acid (RNA) enzymes published in the last five years. Topics discussed include (1) RNA editing by adenosine deamination and its consequences in vivo, (2) ADARs: Enzymes responsible for adenosine to inosine RNA editing and (3) relationship between RNA editing and the microRNA/RNA interface pathways.

Original languageEnglish (US)
Pages (from-to)3397-3411
Number of pages15
JournalChemical Reviews
Volume106
Issue number8
DOIs
StatePublished - Aug 2006
Externally publishedYes

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RNA
Adenosine
Inosine
Adenosine Deaminase
Enzymes
MicroRNAs

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Maydanovych, O., & Beal, P. A. (2006). Breaking the central dogma by RNA editing. Chemical Reviews, 106(8), 3397-3411. https://doi.org/10.1021/cr050314a

Breaking the central dogma by RNA editing. / Maydanovych, Olena; Beal, Peter A.

In: Chemical Reviews, Vol. 106, No. 8, 08.2006, p. 3397-3411.

Research output: Contribution to journalArticle

Maydanovych, O & Beal, PA 2006, 'Breaking the central dogma by RNA editing', Chemical Reviews, vol. 106, no. 8, pp. 3397-3411. https://doi.org/10.1021/cr050314a
Maydanovych, Olena ; Beal, Peter A. / Breaking the central dogma by RNA editing. In: Chemical Reviews. 2006 ; Vol. 106, No. 8. pp. 3397-3411.
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