Brain regions activated by endogenous preparatory set shifting as revealed by fMRI

H. A. Slagter, D. H. Weissman, B. Giesbrecht, J. L. Kenemans, George R Mangun, A. Kok, M. G. Woldorff

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

An ongoing controversy concerns whether executive control mechanisms can actively reconfigure the cognitive system in preparation for switching to a new task set. To address this question, we recorded brain activity from 14 healthy participants, using event-related functional magnetic resonance imaging, while they performed a cued attention task. Critically, in any particular trial, the cued task set was either the same as that in the previous trial or switched. As was hypothesized, cue-related, switch-specific preparatory activity was observed in a network of dorsal frontal and parietal brain areas that are typically associated with cognitive control processes. Moreover, the magnitude of switch-specific preparatory activity varied with the number of possible task sets that could be presented in a given trial block. These findings provide compelling support for the existence of top-down, preparatory control processes that enable set switching. Furthermore, they demonstrate that global task structure is a critical determinant of whether switch-specific preparatory activity is observed.

Original languageEnglish (US)
Pages (from-to)175-189
Number of pages15
JournalCognitive, Affective and Behavioral Neuroscience
Volume6
Issue number3
DOIs
StatePublished - Sep 2006

Fingerprint

Magnetic Resonance Imaging
Executive Function
Brain
Cues
Healthy Volunteers

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Brain regions activated by endogenous preparatory set shifting as revealed by fMRI. / Slagter, H. A.; Weissman, D. H.; Giesbrecht, B.; Kenemans, J. L.; Mangun, George R; Kok, A.; Woldorff, M. G.

In: Cognitive, Affective and Behavioral Neuroscience, Vol. 6, No. 3, 09.2006, p. 175-189.

Research output: Contribution to journalArticle

Slagter, H. A. ; Weissman, D. H. ; Giesbrecht, B. ; Kenemans, J. L. ; Mangun, George R ; Kok, A. ; Woldorff, M. G. / Brain regions activated by endogenous preparatory set shifting as revealed by fMRI. In: Cognitive, Affective and Behavioral Neuroscience. 2006 ; Vol. 6, No. 3. pp. 175-189.
@article{ba6f45d1a9b340caa66b156c5533a698,
title = "Brain regions activated by endogenous preparatory set shifting as revealed by fMRI",
abstract = "An ongoing controversy concerns whether executive control mechanisms can actively reconfigure the cognitive system in preparation for switching to a new task set. To address this question, we recorded brain activity from 14 healthy participants, using event-related functional magnetic resonance imaging, while they performed a cued attention task. Critically, in any particular trial, the cued task set was either the same as that in the previous trial or switched. As was hypothesized, cue-related, switch-specific preparatory activity was observed in a network of dorsal frontal and parietal brain areas that are typically associated with cognitive control processes. Moreover, the magnitude of switch-specific preparatory activity varied with the number of possible task sets that could be presented in a given trial block. These findings provide compelling support for the existence of top-down, preparatory control processes that enable set switching. Furthermore, they demonstrate that global task structure is a critical determinant of whether switch-specific preparatory activity is observed.",
author = "Slagter, {H. A.} and Weissman, {D. H.} and B. Giesbrecht and Kenemans, {J. L.} and Mangun, {George R} and A. Kok and Woldorff, {M. G.}",
year = "2006",
month = "9",
doi = "10.3758/CABN.6.3.175",
language = "English (US)",
volume = "6",
pages = "175--189",
journal = "Cognitive, Affective and Behavioral Neuroscience",
issn = "1530-7026",
publisher = "Springer New York",
number = "3",

}

TY - JOUR

T1 - Brain regions activated by endogenous preparatory set shifting as revealed by fMRI

AU - Slagter, H. A.

AU - Weissman, D. H.

AU - Giesbrecht, B.

AU - Kenemans, J. L.

AU - Mangun, George R

AU - Kok, A.

AU - Woldorff, M. G.

PY - 2006/9

Y1 - 2006/9

N2 - An ongoing controversy concerns whether executive control mechanisms can actively reconfigure the cognitive system in preparation for switching to a new task set. To address this question, we recorded brain activity from 14 healthy participants, using event-related functional magnetic resonance imaging, while they performed a cued attention task. Critically, in any particular trial, the cued task set was either the same as that in the previous trial or switched. As was hypothesized, cue-related, switch-specific preparatory activity was observed in a network of dorsal frontal and parietal brain areas that are typically associated with cognitive control processes. Moreover, the magnitude of switch-specific preparatory activity varied with the number of possible task sets that could be presented in a given trial block. These findings provide compelling support for the existence of top-down, preparatory control processes that enable set switching. Furthermore, they demonstrate that global task structure is a critical determinant of whether switch-specific preparatory activity is observed.

AB - An ongoing controversy concerns whether executive control mechanisms can actively reconfigure the cognitive system in preparation for switching to a new task set. To address this question, we recorded brain activity from 14 healthy participants, using event-related functional magnetic resonance imaging, while they performed a cued attention task. Critically, in any particular trial, the cued task set was either the same as that in the previous trial or switched. As was hypothesized, cue-related, switch-specific preparatory activity was observed in a network of dorsal frontal and parietal brain areas that are typically associated with cognitive control processes. Moreover, the magnitude of switch-specific preparatory activity varied with the number of possible task sets that could be presented in a given trial block. These findings provide compelling support for the existence of top-down, preparatory control processes that enable set switching. Furthermore, they demonstrate that global task structure is a critical determinant of whether switch-specific preparatory activity is observed.

UR - http://www.scopus.com/inward/record.url?scp=33845963802&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33845963802&partnerID=8YFLogxK

U2 - 10.3758/CABN.6.3.175

DO - 10.3758/CABN.6.3.175

M3 - Article

C2 - 17243354

AN - SCOPUS:33845963802

VL - 6

SP - 175

EP - 189

JO - Cognitive, Affective and Behavioral Neuroscience

JF - Cognitive, Affective and Behavioral Neuroscience

SN - 1530-7026

IS - 3

ER -