Bovine immunoglobulin E

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The recognition of homocytotropic antibodies and their occurrence in response to parasite infection preceded the recognition of IgE as a distinct antibody isotype in the bovine species. Passive cutaneous anaphylaxis was an early reliable and antigen specific method to detect IgE in bovine serum. Yet studies on the role of IgE in bovine disease awaited the production of polyclonal and monoclonal antisera specific for the bovine epsilon chain. Applications of antigen specific ELISA and Western blot techniques have demonstrated IgE responses not only to parasite antigens, but also to viral and bacterial pathogens. The role of IgE in vaccine enhanced disease and in eliciting anaphylactic responses to some vaccines has been elucidated using these immunological assays.

Original languageEnglish (US)
Pages (from-to)2-6
Number of pages5
JournalVeterinary Immunology and Immunopathology
Volume132
Issue number1
DOIs
StatePublished - Nov 15 2009

Fingerprint

immunoglobulin E
Immunoglobulin E
antigens
cattle
vaccines
parasites
anaphylaxis
antibodies
cattle diseases
Antigens
blood serum
immunoassays
Vaccines
antiserum
Cattle Diseases
Western blotting
Passive Cutaneous Anaphylaxis
Parasitic Diseases
enzyme-linked immunosorbent assay
Antibodies

Keywords

  • Bovine
  • Homocytotropic antibody
  • IgE
  • IgE assays

ASJC Scopus subject areas

  • Immunology
  • veterinary(all)

Cite this

Bovine immunoglobulin E. / Gershwin, Laurel J.

In: Veterinary Immunology and Immunopathology, Vol. 132, No. 1, 15.11.2009, p. 2-6.

Research output: Contribution to journalArticle

@article{ef836a8b32394a699a2076a0374b90f3,
title = "Bovine immunoglobulin E",
abstract = "The recognition of homocytotropic antibodies and their occurrence in response to parasite infection preceded the recognition of IgE as a distinct antibody isotype in the bovine species. Passive cutaneous anaphylaxis was an early reliable and antigen specific method to detect IgE in bovine serum. Yet studies on the role of IgE in bovine disease awaited the production of polyclonal and monoclonal antisera specific for the bovine epsilon chain. Applications of antigen specific ELISA and Western blot techniques have demonstrated IgE responses not only to parasite antigens, but also to viral and bacterial pathogens. The role of IgE in vaccine enhanced disease and in eliciting anaphylactic responses to some vaccines has been elucidated using these immunological assays.",
keywords = "Bovine, Homocytotropic antibody, IgE, IgE assays",
author = "Gershwin, {Laurel J}",
year = "2009",
month = "11",
day = "15",
doi = "10.1016/j.vetimm.2009.09.008",
language = "English (US)",
volume = "132",
pages = "2--6",
journal = "Veterinary Immunology and Immunopathology",
issn = "0165-2427",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - Bovine immunoglobulin E

AU - Gershwin, Laurel J

PY - 2009/11/15

Y1 - 2009/11/15

N2 - The recognition of homocytotropic antibodies and their occurrence in response to parasite infection preceded the recognition of IgE as a distinct antibody isotype in the bovine species. Passive cutaneous anaphylaxis was an early reliable and antigen specific method to detect IgE in bovine serum. Yet studies on the role of IgE in bovine disease awaited the production of polyclonal and monoclonal antisera specific for the bovine epsilon chain. Applications of antigen specific ELISA and Western blot techniques have demonstrated IgE responses not only to parasite antigens, but also to viral and bacterial pathogens. The role of IgE in vaccine enhanced disease and in eliciting anaphylactic responses to some vaccines has been elucidated using these immunological assays.

AB - The recognition of homocytotropic antibodies and their occurrence in response to parasite infection preceded the recognition of IgE as a distinct antibody isotype in the bovine species. Passive cutaneous anaphylaxis was an early reliable and antigen specific method to detect IgE in bovine serum. Yet studies on the role of IgE in bovine disease awaited the production of polyclonal and monoclonal antisera specific for the bovine epsilon chain. Applications of antigen specific ELISA and Western blot techniques have demonstrated IgE responses not only to parasite antigens, but also to viral and bacterial pathogens. The role of IgE in vaccine enhanced disease and in eliciting anaphylactic responses to some vaccines has been elucidated using these immunological assays.

KW - Bovine

KW - Homocytotropic antibody

KW - IgE

KW - IgE assays

UR - http://www.scopus.com/inward/record.url?scp=70449122137&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70449122137&partnerID=8YFLogxK

U2 - 10.1016/j.vetimm.2009.09.008

DO - 10.1016/j.vetimm.2009.09.008

M3 - Article

VL - 132

SP - 2

EP - 6

JO - Veterinary Immunology and Immunopathology

JF - Veterinary Immunology and Immunopathology

SN - 0165-2427

IS - 1

ER -